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Sleeping Beauty-engineered CAR T cells achieve antileukemic activity without severe toxicities.
Magnani, Chiara F; Gaipa, Giuseppe; Lussana, Federico; Belotti, Daniela; Gritti, Giuseppe; Napolitano, Sara; Matera, Giada; Cabiati, Benedetta; Buracchi, Chiara; Borleri, Gianmaria; Fazio, Grazia; Zaninelli, Silvia; Tettamanti, Sarah; Cesana, Stefania; Colombo, Valentina; Quaroni, Michele; Cazzaniga, Giovanni; Rovelli, Attilio; Biagi, Ettore; Galimberti, Stefania; Calabria, Andrea; Benedicenti, Fabrizio; Montini, Eugenio; Ferrari, Silvia; Introna, Martino; Balduzzi, Adriana; Valsecchi, Maria Grazia; Dastoli, Giuseppe; Rambaldi, Alessandro; Biondi, Andrea.
Afiliação
  • Magnani CF; Tettamanti Research Center, Department of Pediatrics, University of Milano-Bicocca/Fondazione MBBM, Monza, Italy.
  • Gaipa G; Tettamanti Research Center, Department of Pediatrics, University of Milano-Bicocca/Fondazione MBBM, Monza, Italy.
  • Lussana F; Laboratorio di Terapia Cellulare e Genica Stefano Verri, ASST-Monza, Ospedale San Gerardo, Monza, Italy.
  • Belotti D; Hematology and Bone Marrow Transplant Unit, ASST Papa Giovanni XXIII, Bergamo, Italy.
  • Gritti G; Laboratorio di Terapia Cellulare e Genica Stefano Verri, ASST-Monza, Ospedale San Gerardo, Monza, Italy.
  • Napolitano S; Department of Pediatrics, University of Milano-Bicocca, Milan, Italy.
  • Matera G; Hematology and Bone Marrow Transplant Unit, ASST Papa Giovanni XXIII, Bergamo, Italy.
  • Cabiati B; Clinica Pediatrica, University of Milano-Bicocca/Fondazione MBBM, Monza, Italy.
  • Buracchi C; Tettamanti Research Center, Department of Pediatrics, University of Milano-Bicocca/Fondazione MBBM, Monza, Italy.
  • Borleri G; Laboratorio di Terapia Cellulare e Genica Stefano Verri, ASST-Monza, Ospedale San Gerardo, Monza, Italy.
  • Fazio G; Tettamanti Research Center, Department of Pediatrics, University of Milano-Bicocca/Fondazione MBBM, Monza, Italy.
  • Zaninelli S; Laboratorio di Terapia Cellulare e Genica Stefano Verri, ASST-Monza, Ospedale San Gerardo, Monza, Italy.
  • Tettamanti S; Tettamanti Research Center, Department of Pediatrics, University of Milano-Bicocca/Fondazione MBBM, Monza, Italy.
  • Cesana S; Hematology and Bone Marrow Transplant Unit, ASST Papa Giovanni XXIII, Bergamo, Italy.
  • Colombo V; Tettamanti Research Center, Department of Pediatrics, University of Milano-Bicocca/Fondazione MBBM, Monza, Italy.
  • Quaroni M; USS Centro di Terapia Cellulare "G. Lanzani," Bergamo, Italy.
  • Cazzaniga G; Tettamanti Research Center, Department of Pediatrics, University of Milano-Bicocca/Fondazione MBBM, Monza, Italy.
  • Rovelli A; Tettamanti Research Center, Department of Pediatrics, University of Milano-Bicocca/Fondazione MBBM, Monza, Italy.
  • Biagi E; Laboratorio di Terapia Cellulare e Genica Stefano Verri, ASST-Monza, Ospedale San Gerardo, Monza, Italy.
  • Galimberti S; Tettamanti Research Center, Department of Pediatrics, University of Milano-Bicocca/Fondazione MBBM, Monza, Italy.
  • Calabria A; Laboratorio di Terapia Cellulare e Genica Stefano Verri, ASST-Monza, Ospedale San Gerardo, Monza, Italy.
  • Benedicenti F; Tettamanti Research Center, Department of Pediatrics, University of Milano-Bicocca/Fondazione MBBM, Monza, Italy.
  • Montini E; Laboratorio di Terapia Cellulare e Genica Stefano Verri, ASST-Monza, Ospedale San Gerardo, Monza, Italy.
  • Ferrari S; Tettamanti Research Center, Department of Pediatrics, University of Milano-Bicocca/Fondazione MBBM, Monza, Italy.
  • Introna M; Clinica Pediatrica, University of Milano-Bicocca/Fondazione MBBM, Monza, Italy.
  • Balduzzi A; Tettamanti Research Center, Department of Pediatrics, University of Milano-Bicocca/Fondazione MBBM, Monza, Italy.
  • Valsecchi MG; Clinica Pediatrica, University of Milano-Bicocca/Fondazione MBBM, Monza, Italy.
  • Dastoli G; Bicocca Bioinformatics, Biostatistics and Bioimaging Centre, Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
  • Rambaldi A; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET)/IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Biondi A; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET)/IRCCS San Raffaele Scientific Institute, Milan, Italy.
J Clin Invest ; 130(11): 6021-6033, 2020 11 02.
Article em En | MEDLINE | ID: mdl-32780725
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia-Linfoma Linfoblástico de Células Precursoras B / Imunoterapia Adotiva / Transplante de Células-Tronco Hematopoéticas Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: J Clin Invest Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Itália
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia-Linfoma Linfoblástico de Células Precursoras B / Imunoterapia Adotiva / Transplante de Células-Tronco Hematopoéticas Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: J Clin Invest Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Itália