Cpt1a promoted ROS-induced oxidative stress and inflammation in liver injury via the Nrf2/HO-1 and NLRP3 inflammasome signaling pathway.

Luo, Xigang; Sun, Dapeng; Wang, Yinxiang; Zhang, Fengxiang; Wang, Yi

Luo, Xigang; Sun, Dapeng; Wang, Yinxiang; Zhang, Fengxiang; Wang, Yi.

Afiliação

Luo X; Department of Laboratory Medicine, The Third Affiliated Hospital of Jinzhou Medical University, Jinzhou 121000, China.
Sun D; Department of Clinical Pharmacy, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou 121000, China.
Wang Y; Department of Clinical Medicine, Jinzhou Medical University, Jinzhou 121001, China.
Zhang F; Department of Clinical Pharmacy, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou 121000, China.
Wang Y; Department of Blood Transfusion, The Third Affiliated Hospital of Jinzhou Medical University, Jinzhou 121000, China.

Can J Physiol Pharmacol ; 99(5): 468-477, 2021 May.

Article em En | MEDLINE | ID: mdl-32893669

Assuntos

Heme Oxigenase-1; Animais; Inflamassomos/metabolismo; Masculino; Camundongos; Fator 2 Relacionado a NF-E2/metabolismo; Espécies Reativas de Oxigênio/metabolismo

Palavras-chave

Cpt1a; Nrf2/HO-1; ROS; axe Nrf2/HO-1; carnitine palmitoyltransférase 1; dérivés réactifs de l'oxygène; inflammasome; liver injury; lésions hépatiques; oxidative stress; stress oxydatif

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Heme Oxigenase-1 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Can J Physiol Pharmacol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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