Essentiality and Transcriptome-Enriched Pathway Scores Predict Drug-Combination Synergy.

Li, Jin; Huo, Yang; Wu, Xue; Liu, Enze; Zeng, Zhi; Tian, Zhen; Fan, Kunjie; Stover, Daniel; Cheng, Lijun; Li, Lang

Li, Jin; Huo, Yang; Wu, Xue; Liu, Enze; Zeng, Zhi; Tian, Zhen; Fan, Kunjie; Stover, Daniel; Cheng, Lijun; Li, Lang.

Afiliação

Li J; Department of Biomedical Informatics, The Ohio State University, Columbus, OH 43202, USA.
Huo Y; School of Informatics and Computing, Indiana University, Indianapolis, IN 46202, USA.
Wu X; Department of Biomedical Informatics, The Ohio State University, Columbus, OH 43202, USA.
Liu E; School of Informatics and Computing, Indiana University, Indianapolis, IN 46202, USA.
Zeng Z; Department of Biomedical Informatics, The Ohio State University, Columbus, OH 43202, USA.
Tian Z; Department of Biomedical Informatics, The Ohio State University, Columbus, OH 43202, USA.
Fan K; Department of Biomedical Informatics, The Ohio State University, Columbus, OH 43202, USA.
Stover D; Division of Medical Oncology, Department of Medicine, The Ohio State University, Columbus, OH 43202, USA.
Cheng L; Department of Biomedical Informatics, The Ohio State University, Columbus, OH 43202, USA.
Li L; Department of Biomedical Informatics, The Ohio State University, Columbus, OH 43202, USA.

Biology (Basel) ; 9(9)2020 Sep 07.

Article em En | MEDLINE | ID: mdl-32906805

Palavras-chave

KEGG pathway; drug target; drug-combination synergy prediction; gene essentiality; gene expression

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Biology (Basel) Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google