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Single-Cell Genomics Reveals a Novel Cell State During Smooth Muscle Cell Phenotypic Switching and Potential Therapeutic Targets for Atherosclerosis in Mouse and Human.
Pan, Huize; Xue, Chenyi; Auerbach, Benjamin J; Fan, Jiaxin; Bashore, Alexander C; Cui, Jian; Yang, Dina Y; Trignano, Sarah B; Liu, Wen; Shi, Jianting; Ihuegbu, Chinyere O; Bush, Erin C; Worley, Jeremy; Vlahos, Lukas; Laise, Pasquale; Solomon, Robert A; Connolly, Edward S; Califano, Andrea; Sims, Peter A; Zhang, Hanrui; Li, Mingyao; Reilly, Muredach P.
Afiliação
  • Pan H; Division of Cardiology, Department of Medicine (H.P., C.X., A.C.B., J.C., D.Y.Y., S.B.T., W.L., J.S., C.O.I., H.Z., M.P.R.), Columbia University Irving Medical Center, New York.
  • Xue C; Division of Cardiology, Department of Medicine (H.P., C.X., A.C.B., J.C., D.Y.Y., S.B.T., W.L., J.S., C.O.I., H.Z., M.P.R.), Columbia University Irving Medical Center, New York.
  • Auerbach BJ; Graduate Group in Genomics and Computational Biology (B.J.A.), University of Pennsylvania, Philadelphia.
  • Fan J; Department of Biostatistics, Epidemiology, and Informatics (J.F., M.L.), University of Pennsylvania, Philadelphia.
  • Bashore AC; Division of Cardiology, Department of Medicine (H.P., C.X., A.C.B., J.C., D.Y.Y., S.B.T., W.L., J.S., C.O.I., H.Z., M.P.R.), Columbia University Irving Medical Center, New York.
  • Cui J; Division of Cardiology, Department of Medicine (H.P., C.X., A.C.B., J.C., D.Y.Y., S.B.T., W.L., J.S., C.O.I., H.Z., M.P.R.), Columbia University Irving Medical Center, New York.
  • Yang DY; Division of Cardiology, Department of Medicine (H.P., C.X., A.C.B., J.C., D.Y.Y., S.B.T., W.L., J.S., C.O.I., H.Z., M.P.R.), Columbia University Irving Medical Center, New York.
  • Trignano SB; Division of Cardiology, Department of Medicine (H.P., C.X., A.C.B., J.C., D.Y.Y., S.B.T., W.L., J.S., C.O.I., H.Z., M.P.R.), Columbia University Irving Medical Center, New York.
  • Liu W; Division of Cardiology, Department of Medicine (H.P., C.X., A.C.B., J.C., D.Y.Y., S.B.T., W.L., J.S., C.O.I., H.Z., M.P.R.), Columbia University Irving Medical Center, New York.
  • Shi J; Division of Cardiology, Department of Medicine (H.P., C.X., A.C.B., J.C., D.Y.Y., S.B.T., W.L., J.S., C.O.I., H.Z., M.P.R.), Columbia University Irving Medical Center, New York.
  • Ihuegbu CO; Division of Cardiology, Department of Medicine (H.P., C.X., A.C.B., J.C., D.Y.Y., S.B.T., W.L., J.S., C.O.I., H.Z., M.P.R.), Columbia University Irving Medical Center, New York.
  • Bush EC; Department of Systems Biology (E.C.B., J.W., L.V., P.L. A.C., P.A.S.), Columbia University Irving Medical Center, New York.
  • Worley J; Department of Systems Biology (E.C.B., J.W., L.V., P.L. A.C., P.A.S.), Columbia University Irving Medical Center, New York.
  • Vlahos L; Department of Systems Biology (E.C.B., J.W., L.V., P.L. A.C., P.A.S.), Columbia University Irving Medical Center, New York.
  • Laise P; Department of Systems Biology (E.C.B., J.W., L.V., P.L. A.C., P.A.S.), Columbia University Irving Medical Center, New York.
  • Solomon RA; Department of Neurologic Surgery, New York-Presbyterian Hospital/Columbia University Irving Medical Center (R.A.S., E.S.C.).
  • Connolly ES; Department of Neurologic Surgery, New York-Presbyterian Hospital/Columbia University Irving Medical Center (R.A.S., E.S.C.).
  • Califano A; Department of Systems Biology (E.C.B., J.W., L.V., P.L. A.C., P.A.S.), Columbia University Irving Medical Center, New York.
  • Sims PA; Herbert Irving Comprehensive Cancer Center (A.C.), Columbia University Irving Medical Center, New York.
  • Zhang H; JP Sulzberger Columbia Genome Center (A.C.), Columbia University Irving Medical Center, New York.
  • Li M; Department of Biomedical Informatics (A.C.), Columbia University Irving Medical Center, New York.
  • Reilly MP; Department of Biochemistry and Molecular Biophysics (A.C., P.A.S.), Columbia University Irving Medical Center, New York.
Circulation ; 142(21): 2060-2075, 2020 11 24.
Article em En | MEDLINE | ID: mdl-32962412
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenótipo / Diferenciação Celular / Genômica / Miócitos de Músculo Liso / Aterosclerose Limite: Animals / Female / Humans / Male Idioma: En Revista: Circulation Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenótipo / Diferenciação Celular / Genômica / Miócitos de Músculo Liso / Aterosclerose Limite: Animals / Female / Humans / Male Idioma: En Revista: Circulation Ano de publicação: 2020 Tipo de documento: Article