<i>Candida</i> Administration Worsens Cecal Ligation and Puncture-Induced Sepsis in Obese Mice Through Gut Dysbiosis Enhanced Systemic Inflammation, Impact of Pathogen-Associated Molecules From Gut Translocation and Saturated Fatty Acid.

Panpetch, Wimonrat; Sawaswong, Vorthon; Chanchaem, Prangwalai; Ondee, Thunnicha; Dang, Cong Phi; Payungporn, Sunchai; Leelahavanichkul, Asada

Candida Administration Worsens Cecal Ligation and Puncture-Induced Sepsis in Obese Mice Through Gut Dysbiosis Enhanced Systemic Inflammation, Impact of Pathogen-Associated Molecules From Gut Translocation and Saturated Fatty Acid.

Panpetch, Wimonrat; Sawaswong, Vorthon; Chanchaem, Prangwalai; Ondee, Thunnicha; Dang, Cong Phi; Payungporn, Sunchai; Leelahavanichkul, Asada.

Afiliação

Panpetch W; Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Sawaswong V; Program in Bioinformatics and Computational Biology, Graduate School, Chulalongkorn University, Bangkok, Thailand.
Chanchaem P; Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Ondee T; Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Dang CP; Center of Excellence in Systems Biology, Chulalongkorn University, Bangkok, Thailand.
Payungporn S; Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Leelahavanichkul A; Medical Microbiology, Interdisciplinary Program, Graduate School, Chulalongkorn University, Bangkok, Thailand.

Front Immunol ; 11: 561652, 2020.

Article em En | MEDLINE | ID: mdl-33101279

Assuntos

Candida; Disbiose; Ácidos Graxos/metabolismo; Microbioma Gastrointestinal; Mucosa Intestinal/metabolismo; Sepse/etiologia; Sepse/metabolismo; Animais; Linhagem Celular; Contagem de Colônia Microbiana; Dieta Hiperlipídica; Modelos Animais de Doenças; Fezes/microbiologia; Hepatócitos/imunologia; Hepatócitos/metabolismo; Humanos; Mucosa Intestinal/microbiologia; Mucosa Intestinal/patologia; Macrófagos/imunologia; Macrófagos/metabolismo; Camundongos; Camundongos Obesos; Permeabilidade; Probióticos

Palavras-chave

cecal ligation and puncture; dysbiosis; gut leakage; high-fat diet; intestinal Candida; obesity; probiotics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 3_ND Problema de saúde: 3_leprosy / 3_zoonosis Assunto principal: Candida / Sepse / Ácidos Graxos / Disbiose / Microbioma Gastrointestinal / Mucosa Intestinal Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Front Immunol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Tailândia

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