Molecular mimicry in the pathogenesis of rheumatic diseases.
Rheum Dis Clin North Am
; 13(2): 339-52, 1987 Aug.
Article
em En
| MEDLINE
| ID: mdl-3321215
ABSTRACT
Evidence has been presented to support the conclusion that epitope-specific cross-reactive autoimmunity generated in response to a microorganism can result in an inflammatory sequela. The role of this mechanism in the pathogenesis of the experimental disease, adjuvant arthritis, appears clear. In the case of human rheumatic conditions, such as rheumatic fever and the HLA-B27-associated reactive arthritides, the role is not yet established, but clinical evidence suggests that the hypothesis is an attractive one.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Artrite
/
Doenças Autoimunes
Tipo de estudo:
Etiology_studies
Limite:
Humans
Idioma:
En
Revista:
Rheum Dis Clin North Am
Assunto da revista:
REUMATOLOGIA
Ano de publicação:
1987
Tipo de documento:
Article