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Triclosan leads to dysregulation of the metabolic regulator FGF21 exacerbating high fat diet-induced nonalcoholic fatty liver disease.
Yueh, Mei-Fei; He, Feng; Chen, Chen; Vu, Catherine; Tripathi, Anupriya; Knight, Rob; Karin, Michael; Chen, Shujuan; Tukey, Robert H.
Afiliação
  • Yueh MF; Laboratory of Environmental Toxicology, Department of Pharmacology, University of California San Diego, La Jolla, CA 92093.
  • He F; Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California San Diego, La Jolla, CA 92093.
  • Chen C; Laboratory of Environmental Toxicology, Department of Pharmacology, University of California San Diego, La Jolla, CA 92093.
  • Vu C; Laboratory of Environmental Toxicology, Department of Pharmacology, University of California San Diego, La Jolla, CA 92093.
  • Tripathi A; Department of Pediatrics, University of California San Diego, La Jolla, CA 92093.
  • Knight R; Department of Pediatrics, University of California San Diego, La Jolla, CA 92093.
  • Karin M; Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California San Diego, La Jolla, CA 92093; mkarin@health.ucsd.edu rtukey@health.ucsd.edu.
  • Chen S; Laboratory of Environmental Toxicology, Department of Pharmacology, University of California San Diego, La Jolla, CA 92093.
  • Tukey RH; Laboratory of Environmental Toxicology, Department of Pharmacology, University of California San Diego, La Jolla, CA 92093; mkarin@health.ucsd.edu rtukey@health.ucsd.edu.
Proc Natl Acad Sci U S A ; 117(49): 31259-31266, 2020 12 08.
Article em En | MEDLINE | ID: mdl-33229553
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triclosan / PPAR alfa / Fatores de Crescimento de Fibroblastos / Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triclosan / PPAR alfa / Fatores de Crescimento de Fibroblastos / Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article