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Antitumor activity without on-target off-tumor toxicity of GD2-chimeric antigen receptor T cells in patients with neuroblastoma.
Straathof, Karin; Flutter, Barry; Wallace, Rebecca; Jain, Neha; Loka, Thalia; Depani, Sarita; Wright, Gary; Thomas, Simon; Cheung, Gordon Weng-Kit; Gileadi, Talia; Stafford, Sian; Kokalaki, Evangelia; Barton, Jack; Marriott, Clare; Rampling, Dyanne; Ogunbiyi, Olumide; Akarca, Ayse U; Marafioti, Teresa; Inglott, Sarah; Gilmour, Kimberly; Al-Hajj, Muhammad; Day, William; McHugh, Kieran; Biassoni, Lorenzo; Sizer, Natalie; Barton, Claire; Edwards, David; Dragoni, Ilaria; Silvester, Julie; Dyer, Karen; Traub, Stephanie; Elson, Lily; Brook, Sue; Westwood, Nigel; Robson, Lesley; Bedi, Ami; Howe, Karen; Barry, Ailish; Duncan, Catriona; Barone, Giuseppe; Pule, Martin; Anderson, John.
Afiliação
  • Straathof K; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 1EH, UK.
  • Flutter B; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
  • Wallace R; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 1EH, UK.
  • Jain N; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
  • Loka T; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 1EH, UK.
  • Depani S; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
  • Wright G; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
  • Thomas S; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
  • Cheung GW; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
  • Gileadi T; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
  • Stafford S; UCL Cancer Institute, London WC1E 6DD, UK.
  • Kokalaki E; Autolus Ltd., London W12 7FP, UK.
  • Barton J; UCL Cancer Institute, London WC1E 6DD, UK.
  • Marriott C; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 1EH, UK.
  • Rampling D; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 1EH, UK.
  • Ogunbiyi O; UCL Cancer Institute, London WC1E 6DD, UK.
  • Akarca AU; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 1EH, UK.
  • Marafioti T; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
  • Inglott S; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
  • Gilmour K; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
  • Al-Hajj M; UCL Cancer Institute, London WC1E 6DD, UK.
  • Day W; UCL Cancer Institute, London WC1E 6DD, UK.
  • McHugh K; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
  • Biassoni L; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
  • Sizer N; Autolus Ltd., London W12 7FP, UK.
  • Barton C; Autolus Ltd., London W12 7FP, UK.
  • Edwards D; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
  • Dragoni I; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
  • Silvester J; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
  • Dyer K; Centre for Drug Development, Cancer Research UK, London E20 1JQ, UK.
  • Traub S; Centre for Drug Development, Cancer Research UK, London E20 1JQ, UK.
  • Elson L; Centre for Drug Development, Cancer Research UK, London E20 1JQ, UK.
  • Brook S; Centre for Drug Development, Cancer Research UK, London E20 1JQ, UK.
  • Westwood N; Centre for Drug Development, Cancer Research UK, London E20 1JQ, UK.
  • Robson L; Centre for Drug Development, Cancer Research UK, London E20 1JQ, UK.
  • Bedi A; Centre for Drug Development, Cancer Research UK, London E20 1JQ, UK.
  • Howe K; Centre for Drug Development, Cancer Research UK, London E20 1JQ, UK.
  • Barry A; Centre for Drug Development, Cancer Research UK, London E20 1JQ, UK.
  • Duncan C; Centre for Drug Development, Cancer Research UK, London E20 1JQ, UK.
  • Barone G; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
  • Pule M; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
  • Anderson J; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
Sci Transl Med ; 12(571)2020 11 25.
Article em En | MEDLINE | ID: mdl-33239386
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Antígenos Quiméricos / Neuroblastoma Limite: Child / Humans Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Antígenos Quiméricos / Neuroblastoma Limite: Child / Humans Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido