Relation of Poor Nutritional Status to Mild Cognitive Impairment in Patients with Coronary Artery Disease.
J Nutr Health Aging
; 24(10): 1080-1086, 2020.
Article
em En
| MEDLINE
| ID: mdl-33244564
ABSTRACT
OBJECTIVES:
Nutritional status affects cerebral circulation and cognitive function. More attention needs to be paid to nutritional status in coronary artery disease (CAD) patients, yet the relation between nutritional status or dietary intake (DI) and cognitive function or mild cognitive impairment (MCI) in CAD patients remain unclear. Thus, we examined the following relations 1) that between nutritional status and cognitive function, and MCI and 2) that between DI and cognitive function, and MCI. DESIGN, SETTING, ANDPARTICIPANTS:
We conducted a cross-sectional study of 208 patients with CAD but without dementia. MEASUREMENTS MCI was estimated with the Japanese version of the Montreal Cognitive Assessment (MoCA-J). Nutritional status was assessed by the Geriatric Nutritional Risk Index (GNRI), and DI was assessed by total energy intake per day. We investigated the relation between nutritional status or DI and cognitive function by Pearson correlation analysis, and that between nutritional status or DI and MCI by multivariable logistic regression analysis.RESULTS:
The GNRI and DI were positively associated with the MoCA-J score (r = 0.23, p < 0.001, and r = 0.24, p < 0.001, respectively), and both were independently associated with MCI in the multivariable logistic regression analysis (odds ratio, 0.96; p = 0.045, and odds ratio, 0.998; p = 0.020, respectively).CONCLUSIONS:
Poor nutritional status and low DI were found to be significantly associated with cognitive function and MCI in CAD patients. Our findings regarding nutritional status and DI might be useful for clinicians to prevent or intervene in the early cognitive decline of inpatients with CAD.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença da Artéria Coronariana
/
Estado Nutricional
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Desnutrição
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Disfunção Cognitiva
Tipo de estudo:
Observational_studies
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Prevalence_studies
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Risk_factors_studies
Aspecto:
Determinantes_sociais_saude
Limite:
Aged
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
J Nutr Health Aging
Assunto da revista:
CIENCIAS DA NUTRICAO
/
GERIATRIA
Ano de publicação:
2020
Tipo de documento:
Article