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Methylnaltrexone crosses the blood-brain barrier and attenuates centrally-mediated behavioral effects of morphine and oxycodone in mice.
Walentiny, D Matthew; Komla, Essie; Moisa, Léa T; Mustafa, Mohammed A; Poklis, Justin L; Akbarali, Hamid I; Beardsley, Patrick M.
Afiliação
  • Walentiny DM; Department of Pharmacology & Toxicology, Virginia Commonwealth University, 1217 E. Marshall Street, Richmond, VA, 23298-0613, USA. Electronic address: david.walentiny@vcuhealth.org.
  • Komla E; Department of Pharmacology & Toxicology, Virginia Commonwealth University, 1217 E. Marshall Street, Richmond, VA, 23298-0613, USA.
  • Moisa LT; Department of Pharmacology & Toxicology, Virginia Commonwealth University, 1217 E. Marshall Street, Richmond, VA, 23298-0613, USA.
  • Mustafa MA; Department of Pharmacology & Toxicology, Virginia Commonwealth University, 1217 E. Marshall Street, Richmond, VA, 23298-0613, USA.
  • Poklis JL; Department of Pharmacology & Toxicology, Virginia Commonwealth University, 1217 E. Marshall Street, Richmond, VA, 23298-0613, USA.
  • Akbarali HI; Department of Pharmacology & Toxicology, Virginia Commonwealth University, 1217 E. Marshall Street, Richmond, VA, 23298-0613, USA.
  • Beardsley PM; Department of Pharmacology & Toxicology, Virginia Commonwealth University, 1217 E. Marshall Street, Richmond, VA, 23298-0613, USA; Institute for Drug and Alcohol Studies & Center for Biomarker Research and Precision Medicine, Virginia Commonwealth University, 410 N. 12th Street, PO Box 98061
Neuropharmacology ; 185: 108437, 2021 03 01.
Article em En | MEDLINE | ID: mdl-33316279
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxicodona / Barreira Hematoencefálica / Analgésicos Opioides / Morfina / Naltrexona / Antagonistas de Entorpecentes Limite: Animals Idioma: En Revista: Neuropharmacology Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxicodona / Barreira Hematoencefálica / Analgésicos Opioides / Morfina / Naltrexona / Antagonistas de Entorpecentes Limite: Animals Idioma: En Revista: Neuropharmacology Ano de publicação: 2021 Tipo de documento: Article