Primary cutaneous malignant melanoma in Rett syndrome: Report of a case with nuclear features resembling herpes simplex virus cytopathic effects-a hitherto unrecognized morphological variant.
J Cutan Pathol
; 48(7): 908-910, 2021 Jul.
Article
em En
| MEDLINE
| ID: mdl-33345376
ABSTRACT
Rett syndrome (RTT) is a progressive neurological disorder, affecting females with mutations in the X-linked gene methyl-CpG-binding protein 2 (MECP2). While MECP2 has been implicated in cancers of the breast, colon, and prostrate, cancer in patients with RTT is rare. We present a case of malignant melanoma in a patient with RTT, which additionally, displayed hitherto undescribed nuclear features, resembling herpes simplex virus cytopathic effects.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
/
Síndrome de Rett
/
Simplexvirus
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Efeito Citopatogênico Viral
/
Melanoma
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
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Female
/
Humans
Idioma:
En
Revista:
J Cutan Pathol
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Reino Unido