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Design, synthesis, biological evaluation and molecular docking of new 1,3,4-oxadiazole homonucleosides and their double-headed analogs as antitumor agents.
El Mansouri, Az-Eddine; Oubella, Ali; Mehdi, Ahmad; AitItto, Moulay Youssef; Zahouily, Mohamed; Morjani, Hamid; Lazrek, Hassan B.
Afiliação
  • El Mansouri AE; Laboratoire de Materiaux, Catalyse & Valorisation des Ressources Naturelles, URAC 24, Faculte des Sciences et Techniques, Universite Hassan II, Casablanca, Morocco; Laboratory of Biomolecular and Medicinal Chemistry, Department of Chemistry, Faculty of Science Semlalia, BP 2390, Marrakech 40001,
  • Oubella A; Laboratoire de Synthèse Organique et de Physico-Chimie Moléculaire, Département de Chimie, Faculte ́ des Sciences, Semlalia BP 2390, Marrakech 40001, Morocco.
  • Mehdi A; Institut Charles Gerhardt Montpellier, UMR 5253, CNRS-UM-ENSCM, Université de Montpellier, Montpellier cedex 5, France.
  • AitItto MY; Laboratoire de Synthèse Organique et de Physico-Chimie Moléculaire, Département de Chimie, Faculte ́ des Sciences, Semlalia BP 2390, Marrakech 40001, Morocco.
  • Zahouily M; Laboratoire de Materiaux, Catalyse & Valorisation des Ressources Naturelles, URAC 24, Faculte des Sciences et Techniques, Universite Hassan II, Casablanca, Morocco; Moroccan Foundation for Advanced Science, Innovation and Research (MAScIR), VARENA Center, Rue Mohamed El Jazouli, Madinat Al Irfan
  • Morjani H; BioSpecT - EA7506 UFR de Pharmacie, Univ-Reims 51, rue Cognacq Jay, 51096 Reims cedex, France. Electronic address: hamid.morjani@univ-reims.fr.
  • Lazrek HB; Laboratory of Biomolecular and Medicinal Chemistry, Department of Chemistry, Faculty of Science Semlalia, BP 2390, Marrakech 40001, Morocco. Electronic address: hblazrek50@gmail.com.
Bioorg Chem ; 108: 104558, 2021 03.
Article em En | MEDLINE | ID: mdl-33358270
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxidiazóis / Desenho de Fármacos / Simulação de Acoplamento Molecular / Antineoplásicos / Nucleosídeos Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxidiazóis / Desenho de Fármacos / Simulação de Acoplamento Molecular / Antineoplásicos / Nucleosídeos Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2021 Tipo de documento: Article