Chronic Lorcaserin Treatment Reverses the Nicotine Withdrawal-Induced Disruptions to Behavior and Maturation in Developing Neurons in the Hippocampus of Rats.

Zaniewska, Magdalena; Nikiforuk, Agnieszka; Glowacka, Urszula; Brygider, Sabina; Wesolowska, Julita; Litwa, Ewa; Mackowiak, Marzena

Zaniewska, Magdalena; Nikiforuk, Agnieszka; Glowacka, Urszula; Brygider, Sabina; Wesolowska, Julita; Litwa, Ewa; Mackowiak, Marzena.

Afiliação

Zaniewska M; Maj Institute of Pharmacology, Polish Academy of Sciences, Department of Pharmacology, Laboratory of Pharmacology and Brain Biostructure, 12 Smetna Street, 31-343 Kraków, Poland.
Nikiforuk A; Maj Institute of Pharmacology, Polish Academy of Sciences, Department of Behavioral Neuroscience and Drug Development, 12 Smetna Street, 31-343 Kraków, Poland.
Glowacka U; Maj Institute of Pharmacology, Polish Academy of Sciences, Department of Pharmacology, Laboratory of Pharmacology and Brain Biostructure, 12 Smetna Street, 31-343 Kraków, Poland.
Brygider S; Maj Institute of Pharmacology, Polish Academy of Sciences, Department of Pharmacology, Laboratory of Pharmacology and Brain Biostructure, 12 Smetna Street, 31-343 Kraków, Poland.
Wesolowska J; Maj Institute of Pharmacology, Polish Academy of Sciences, Laboratory of In Vivo and In Vitro Imaging, 12 Smetna Street, 31-343 Kraków, Poland.
Litwa E; Maj Institute of Pharmacology, Polish Academy of Sciences, Department of Behavioral Neuroscience and Drug Development, 12 Smetna Street, 31-343 Kraków, Poland.
Mackowiak M; Maj Institute of Pharmacology, Polish Academy of Sciences, Department of Pharmacology, Laboratory of Pharmacology and Brain Biostructure, 12 Smetna Street, 31-343 Kraków, Poland.

Int J Mol Sci ; 22(2)2021 Jan 16.

Article em En | MEDLINE | ID: mdl-33467149

Assuntos

Benzazepinas/uso terapêutico; Hipocampo/efeitos dos fármacos; Nicotina/efeitos adversos; Agonistas do Receptor de Serotonina/uso terapêutico; Síndrome de Abstinência a Substâncias/tratamento farmacológico; Animais; Benzazepinas/administração & dosagem; Benzazepinas/farmacologia; Proteína Duplacortina; Comportamento de Procura de Droga; Hipocampo/citologia; Hipocampo/crescimento & desenvolvimento; Locomoção; Masculino; Neurônios/citologia; Neurônios/efeitos dos fármacos; Ratos; Ratos Sprague-Dawley; Agonistas do Receptor de Serotonina/administração & dosagem; Agonistas do Receptor de Serotonina/farmacologia

Palavras-chave

5-HT2C receptor; adult hippocampal neurogenesis; forced swim test; nicotine self-administration; novel object recognition; rat

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome de Abstinência a Substâncias / Benzazepinas / Agonistas do Receptor de Serotonina / Hipocampo / Nicotina Limite: Animals Idioma: En Revista: Int J Mol Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Polônia

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