Thiamine fortification strategies in low- and middle-income settings: a review.
Ann N Y Acad Sci
; 1498(1): 29-45, 2021 08.
Article
em En
| MEDLINE
| ID: mdl-33496051
ABSTRACT
Thiamine (vitamin B1 ) is an essential micronutrient in energy metabolism and cognitive and neurological health. Thiamine deficiency disorders (TDDs) have a range of clinical presentations that result in various morbidities and can be fatal if not promptly recognized and treated, especially in infants. To intervene, thiamine intakes by breastfeeding mothers and others at risk of thiamine deficiency should be increased to ensure adequate thiamine intake. Although thiamine fortification programs have a long history in high-income countries, there are few mandatory fortification programs to address TDDs in low- and middle-income countries (LMICs), particularly in the regions of greatest concern, South and Southeast Asia. This review highlights essential aspects for consideration in the development of a mandatory fortification program in LMICs, including an overview of the data required to model fortification dosing schemes, available thiamine fortificants, and potential fortification vehicles, as well as identifies current knowledge gaps.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Contexto em Saúde:
11_ODS3_cobertura_universal
/
2_ODS3
Problema de saúde:
11_delivery_arrangements
/
11_multisectoral_coordination
/
2_cobertura_universal
Assunto principal:
Tiamina
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Deficiência de Tiamina
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Alimentos Fortificados
/
Suplementos Nutricionais
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Screening_studies
Limite:
Humans
Idioma:
En
Revista:
Ann N Y Acad Sci
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Canadá