[Association between serum albumin level and health-related quality of life in Hainan centenarians: a cross-sectional study].

ABSTRACT

Objective: To investigate the association between serum albumin levels and health-related quality of life in centenarians in Hainan province, China. Methods: We conducted a full sample centenarian cohort study in a community population in Hainan from 2014 to 2016, which included 1 002 centenarians for questionnaire surveys, physical examinations and biological tests. The EQ-5D-VAS scale was used to evaluate health-related quality of life, and multiple linear regression and multiple logistic regression analyses were used to analyze the association between serum albumin levels and health-related quality of life. Results: There was a positive linear relationship between serum albumin levels and EQ-5D/VAS score. The normalized ß values in the fully adjusted model was 0.156 (P<0.001). In the multivariate logistic regression analysis, after fully adjusting the covariates, the risk of health related life quality impairment in the lower albumin group was 2.369 times(95%CI 1.424-3.939) than that in the higher albumin group. Gender stratified analyses showed that the OR was 4.406 (95%CI 1.537-12.631) in male centenarians and 2.035 (95%CI 1.125-3.680) in female centenarians. Conclusion: Lower serum albumin level was associated with impaired health-related quality of life in centenarians in Hainan.