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The C3/465 glycan hole cluster in BG505 HIV-1 envelope is the major neutralizing target involved in preventing mucosal SHIV infection.
Charles, Tysheena P; Burton, Samantha L; Arunachalam, Prabhu S; Cottrell, Christopher A; Sewall, Leigh M; Bollimpelli, Venkata S; Gangadhara, Sailaja; Dey, Antu K; Ward, Andrew B; Shaw, George M; Hunter, Eric; Amara, Rama R; Pulendran, Bali; van Gils, Marit J; Derdeyn, Cynthia A.
Afiliação
  • Charles TP; Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America.
  • Burton SL; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
  • Arunachalam PS; Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America.
  • Cottrell CA; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
  • Sewall LM; Departments of Pathology, and Microbiology and Immunology, Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, California, United States of America.
  • Bollimpelli VS; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
  • Gangadhara S; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
  • Dey AK; Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America.
  • Ward AB; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
  • Shaw GM; Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America.
  • Hunter E; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
  • Amara RR; International AIDS Vaccine Initiative, New York, New York, United States of America.
  • Pulendran B; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
  • van Gils MJ; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • Derdeyn CA; Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America.
PLoS Pathog ; 17(2): e1009257, 2021 02.
Article em En | MEDLINE | ID: mdl-33556148

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 1_ASSA2030 / 2_ODS3 Problema de saúde: 1_doencas_transmissiveis / 2_enfermedades_transmissibles Assunto principal: Polissacarídeos / Anticorpos Anti-HIV / Síndrome de Imunodeficiência Adquirida dos Símios / HIV-1 / Vírus da Imunodeficiência Símia / Produtos do Gene env do Vírus da Imunodeficiência Humana / Anticorpos Neutralizantes Limite: Animals / Female / Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 1_ASSA2030 / 2_ODS3 Problema de saúde: 1_doencas_transmissiveis / 2_enfermedades_transmissibles Assunto principal: Polissacarídeos / Anticorpos Anti-HIV / Síndrome de Imunodeficiência Adquirida dos Símios / HIV-1 / Vírus da Imunodeficiência Símia / Produtos do Gene env do Vírus da Imunodeficiência Humana / Anticorpos Neutralizantes Limite: Animals / Female / Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
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