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Elevated levels of mitochondrial CoQ10 induce ROS-mediated apoptosis in pancreatic cancer.
Dadali, Tulin; Diers, Anne R; Kazerounian, Shiva; Muthuswamy, Senthil K; Awate, Pallavi; Ng, Ryan; Mogre, Saie; Spencer, Carrie; Krumova, Katerina; Rockwell, Hannah E; McDaniel, Justice; Chen, Emily Y; Gao, Fei; Diedrich, Karl T; Vemulapalli, Vijetha; Rodrigues, Leonardo O; Akmaev, Viatcheslav R; Thapa, Khampaseuth; Hidalgo, Manuel; Bose, Arindam; Vishnudas, Vivek K; Moser, A James; Granger, Elder; Kiebish, Michael A; Gesta, Stephane; Narain, Niven R; Sarangarajan, Rangaprasad.
Afiliação
  • Dadali T; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Diers AR; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Kazerounian S; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Muthuswamy SK; Department of Medicine, Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USA.
  • Awate P; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Ng R; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Mogre S; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Spencer C; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Krumova K; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Rockwell HE; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • McDaniel J; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Chen EY; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Gao F; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Diedrich KT; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Vemulapalli V; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Rodrigues LO; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Akmaev VR; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Thapa K; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Hidalgo M; Department of Medicine, Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USA.
  • Bose A; Department of Medicine, Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USA.
  • Vishnudas VK; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Moser AJ; Department of Medicine, Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USA.
  • Granger E; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Kiebish MA; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Gesta S; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Narain NR; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA.
  • Sarangarajan R; BERG LLC, 500 Old Connecticut Path, Bldg B, 3rd Floor, Framingham, MA, 01710, USA. Rangaprasad.Sarangarajan@BergHealth.com.
Sci Rep ; 11(1): 5749, 2021 03 11.
Article em En | MEDLINE | ID: mdl-33707480
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 6_endocrine_disorders / 6_pancreatic_cancer Assunto principal: Neoplasias Pancreáticas / Ubiquinona / Espécies Reativas de Oxigênio / Apoptose / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 6_endocrine_disorders / 6_pancreatic_cancer Assunto principal: Neoplasias Pancreáticas / Ubiquinona / Espécies Reativas de Oxigênio / Apoptose / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos