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Time-resolved systems immunology reveals a late juncture linked to fatal COVID-19.
Liu, Can; Martins, Andrew J; Lau, William W; Rachmaninoff, Nicholas; Chen, Jinguo; Imberti, Luisa; Mostaghimi, Darius; Fink, Danielle L; Burbelo, Peter D; Dobbs, Kerry; Delmonte, Ottavia M; Bansal, Neha; Failla, Laura; Sottini, Alessandra; Quiros-Roldan, Eugenia; Han, Kyu Lee; Sellers, Brian A; Cheung, Foo; Sparks, Rachel; Chun, Tae-Wook; Moir, Susan; Lionakis, Michail S; Rossi, Camillo; Su, Helen C; Kuhns, Douglas B; Cohen, Jeffrey I; Notarangelo, Luigi D; Tsang, John S.
Afiliação
  • Liu C; Multiscale Systems Biology Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD 20892, USA; Graduate Program in Biological Sciences, University of Maryland, College Park, MD 20742, USA.
  • Martins AJ; Multiscale Systems Biology Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD 20892, USA.
  • Lau WW; Multiscale Systems Biology Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD 20892, USA; Office of Intramural Research, CIT, NIH, Bethesda, MD 20892, USA.
  • Rachmaninoff N; Multiscale Systems Biology Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD 20892, USA; Graduate Program in Biological Sciences, University of Maryland, College Park, MD 20742, USA.
  • Chen J; NIH Center for Human Immunology, NIAID, NIH, Bethesda, MD 20892, USA.
  • Imberti L; CREA Laboratory, Diagnostic Department, ASST Spedali Civili di Brescia, Brescia 25123, Italy.
  • Mostaghimi D; Multiscale Systems Biology Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD 20892, USA.
  • Fink DL; Neutrophil Monitoring Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD 20701, USA.
  • Burbelo PD; National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD 20892, USA.
  • Dobbs K; Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD 20892, USA.
  • Delmonte OM; Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD 20892, USA.
  • Bansal N; Multiscale Systems Biology Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD 20892, USA.
  • Failla L; Multiscale Systems Biology Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD 20892, USA.
  • Sottini A; CREA Laboratory, Diagnostic Department, ASST Spedali Civili di Brescia, Brescia 25123, Italy.
  • Quiros-Roldan E; Department of Infectious and Tropical Diseases, University of Brescia and ASST Spedali Civili di Brescia, Brescia 25123, Italy.
  • Han KL; NIH Center for Human Immunology, NIAID, NIH, Bethesda, MD 20892, USA.
  • Sellers BA; NIH Center for Human Immunology, NIAID, NIH, Bethesda, MD 20892, USA.
  • Cheung F; NIH Center for Human Immunology, NIAID, NIH, Bethesda, MD 20892, USA.
  • Sparks R; Multiscale Systems Biology Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD 20892, USA.
  • Chun TW; Laboratory of Immunoregulation, NIAID, NIH, Bethesda, MD 20892, USA.
  • Moir S; Laboratory of Immunoregulation, NIAID, NIH, Bethesda, MD 20892, USA.
  • Lionakis MS; Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD 20892, USA.
  • Rossi C; ASST Spedali Civili di Brescia, Brescia 25123, Italy.
  • Su HC; Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD 20892, USA.
  • Kuhns DB; Neutrophil Monitoring Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD 20701, USA.
  • Cohen JI; Laboratory of Infectious Diseases, NIAID, NIH, Bethesda, MD 20892, USA.
  • Notarangelo LD; Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD 20892, USA.
  • Tsang JS; Multiscale Systems Biology Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD 20892, USA; NIH Center for Human Immunology, NIAID, NIH, Bethesda, MD 20892, USA. Electronic address: john.tsang@nih.gov.
Cell ; 184(7): 1836-1857.e22, 2021 04 01.
Article em En | MEDLINE | ID: mdl-33713619
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 4_TD / 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 4_covid_19 / 4_pneumonia / 6_other_respiratory_diseases Assunto principal: Índice de Gravidade de Doença / Células Dendríticas / Células Matadoras Naturais / Expressão Gênica / Citocinas / COVID-19 Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Cell Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 4_TD / 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 4_covid_19 / 4_pneumonia / 6_other_respiratory_diseases Assunto principal: Índice de Gravidade de Doença / Células Dendríticas / Células Matadoras Naturais / Expressão Gênica / Citocinas / COVID-19 Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Cell Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos