Development of biliary stent applying the antibacterial activity of silver: A literature review.
Biomed Mater Eng
; 32(2): 63-71, 2021.
Article
em En
| MEDLINE
| ID: mdl-33720871
ABSTRACT
BACKGROUND:
Endoscopic transpapillary stenting is commonly performed in patients with obstructive jaundice caused by a biliary stricture. Although the plastic stent (PS) is widely used for biliary drainage because of the low-cost and easy procedure, patency is short after placement in the bile duct because of the small diameter. Dysfunction of PS is primarily caused by biliary sludge that forms as a result of bacterial adhesion and subsequent biofilm formation on the inner surface of the stent. It is well known that silver ions have excellent antibacterial activity against a wide range of microorganisms.OBJECTIVE:
This review provides an overview and perspective of the significance of silver-coated biliary stents.METHODS:
We collected literature regarding silver-coated biliary stents, reviewed the current research/development status and discussed their possible usefulness.RESULTS:
To date, several in vivo/vitro studies evaluated the patency of silver-blended or silver-coated biliary stents. These studies suggested that the silver coating on a PS was likely to prolong the patency period.CONCLUSION:
The development of biliary stents using silver is expected to prolong stent patency and prevent frequent stent replacement.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Prata
Limite:
Humans
Idioma:
En
Revista:
Biomed Mater Eng
Assunto da revista:
BIOTECNOLOGIA
/
ENGENHARIA BIOMEDICA
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Japão