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The AMPK modulator metformin as adjunct to methotrexate in patients with rheumatoid arthritis: A proof-of-concept, randomized, double-blind, placebo-controlled trial.
Abdallah, Mahmoud S; Alarfaj, Sumaiah J; Saif, Dalia S; El-Naggar, Mostafa E; Elsokary, Mohamed A; Elsawah, Hozaifa K; Abdelsattar Zaki, Shimaa; Wahsh, Engy A; Abo Mansour, Hend E; Mosalam, Esraa M.
Afiliação
  • Abdallah MS; Department of Clinical Pharmacy, Faculty of Pharmacy, University of Sadat City, Sadat City, Menoufia 32897, Egypt. Electronic address: Mahmoud.samy@fop.usc.edu.eg.
  • Alarfaj SJ; Department of Pharmacy Practice, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Saudi Arabia.
  • Saif DS; Department of Physical Medicine, Rheumatology and Rehabilitation, Faculty of Medicine, Menoufia University, Menoufia, Egypt.
  • El-Naggar ME; Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Sadat City, Menoufia, Egypt.
  • Elsokary MA; Department of Biostatistics, High Institute of Public Health, Alexandria University, Alexandria, Egypt.
  • Elsawah HK; Department of Biostatistics, High Institute of Public Health, Alexandria University, Alexandria, Egypt.
  • Abdelsattar Zaki S; Department of Clinical Biochemistry and Molecular Diagnostics, National Liver Institute, Menoufia University, Egypt.
  • Wahsh EA; Department of Clinical Pharmacy, Faculty of Pharmacy, October 6 University, Egypt.
  • Abo Mansour HE; Department of Biochemistry, Faculty of Pharmacy, Menoufia University, Egypt.
  • Mosalam EM; Department of Biochemistry, Faculty of Pharmacy, Menoufia University, Egypt.
Int Immunopharmacol ; 95: 107575, 2021 Jun.
Article em En | MEDLINE | ID: mdl-33773207
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 1_ASSA2030 Problema de saúde: 1_doencas_nao_transmissiveis Assunto principal: Artrite Reumatoide / Adjuvantes Imunológicos / Metotrexato / Antirreumáticos / Proteínas Quinases Ativadas por AMP / Metformina Tipo de estudo: Clinical_trials Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Int Immunopharmacol Assunto da revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 1_ASSA2030 Problema de saúde: 1_doencas_nao_transmissiveis Assunto principal: Artrite Reumatoide / Adjuvantes Imunológicos / Metotrexato / Antirreumáticos / Proteínas Quinases Ativadas por AMP / Metformina Tipo de estudo: Clinical_trials Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Int Immunopharmacol Assunto da revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article