A potent neutralizing nanobody against SARS-CoV-2 with inhaled delivery potential.

Gai, Junwei; Ma, Linlin; Li, Guanghui; Zhu, Min; Qiao, Peng; Li, Xiaofei; Zhang, Haiwei; Zhang, Yanmin; Chen, Yadong; Ji, Weiwei; Zhang, Hao; Cao, Huanhuan; Li, Xionghui; Gong, Rui; Wan, Yakun

Gai, Junwei; Ma, Linlin; Li, Guanghui; Zhu, Min; Qiao, Peng; Li, Xiaofei; Zhang, Haiwei; Zhang, Yanmin; Chen, Yadong; Ji, Weiwei; Zhang, Hao; Cao, Huanhuan; Li, Xionghui; Gong, Rui; Wan, Yakun.

Afiliação

Gai J; Shanghai Novamab Biopharmaceuticals Co., Ltd Shanghai China.
Ma L; Shanghai Key Laboratory of Molecular Imaging Shanghai University of Medicine and Health Sciences Shanghai China.
Li G; Shanghai Novamab Biopharmaceuticals Co., Ltd Shanghai China.
Zhu M; Shanghai Novamab Biopharmaceuticals Co., Ltd Shanghai China.
Qiao P; Shanghai Novamab Biopharmaceuticals Co., Ltd Shanghai China.
Li X; Shanghai Novamab Biopharmaceuticals Co., Ltd Shanghai China.
Zhang H; CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science Chinese Academy of Sciences Wuhan China.
Zhang Y; Laboratory of Molecular Design and Drug Discovery, School of Science China Pharmaceutical University Nanjing China.
Chen Y; Laboratory of Molecular Design and Drug Discovery, School of Science China Pharmaceutical University Nanjing China.
Ji W; Shanghai Novamab Biopharmaceuticals Co., Ltd Shanghai China.
Zhang H; Shanghai Novamab Biopharmaceuticals Co., Ltd Shanghai China.
Cao H; Shanghai Novamab Biopharmaceuticals Co., Ltd Shanghai China.
Li X; Shanghai Novamab Biopharmaceuticals Co., Ltd Shanghai China.
Gong R; CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science Chinese Academy of Sciences Wuhan China.
Wan Y; Shanghai Novamab Biopharmaceuticals Co., Ltd Shanghai China.

MedComm (2020) ; 2(1): 101-113, 2021 Mar.

Article em En | MEDLINE | ID: mdl-33821254

Palavras-chave

SARSCoV2; largescale production; nanobody; nebulization; neutralizing activity

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: MedComm (2020) Ano de publicação: 2021 Tipo de documento: Article