Immunological underpinnings of Ascaris infection, reinfection and co-infection and their associated co-morbidities.
Parasitology
; : 1-10, 2021 Apr 12.
Article
em En
| MEDLINE
| ID: mdl-33843506
ABSTRACT
Human ascariasis is the most common and prevalent neglected tropical disease and is estimated that ~819 million people are infected around the globe, accounting for 0.861 million years of disability-adjusted life years in 2017. Even with the existence of highly effective drugs, the constant presence of infective parasite eggs in the environment contribute to a high reinfection rate after treatment. Due to its high prevalence and broad geographic distribution Ascaris infection is associated with a variety of co-morbidities and co-infections. Here, we provide data from both experimental models and humans studies that illustrate how complex is the interaction of Ascaris with the host immune system, especially, in the context of reinfections, co-infections and associated co-morbidities.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Contexto em Saúde:
3_ND
Problema de saúde:
3_neglected_diseases
Tipo de estudo:
Risk_factors_studies
Aspecto:
Patient_preference
Idioma:
En
Revista:
Parasitology
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Brasil