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Elucidation of metabolic pathways of 25-hydroxyvitamin D3 mediated by CYP24A1 and CYP3A using Cyp24a1 knockout rats generated by CRISPR/Cas9 system.
Yasuda, Kaori; Nishikawa, Miyu; Okamoto, Kairi; Horibe, Kyohei; Mano, Hiroki; Yamaguchi, Mana; Okon, Risa; Nakagawa, Kimie; Tsugawa, Naoko; Okano, Toshio; Kawagoe, Fumihiro; Kittaka, Atsushi; Ikushiro, Shinichi; Sakaki, Toshiyuki.
Afiliação
  • Yasuda K; Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, Imizu, Toyama, Japan.
  • Nishikawa M; Department of Biotechnology, Faculty of Engineering, Toyama Prefectural University, Imizu, Toyama, Japan.
  • Okamoto K; Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, Imizu, Toyama, Japan.
  • Horibe K; Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, Imizu, Toyama, Japan.
  • Mano H; Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, Imizu, Toyama, Japan.
  • Yamaguchi M; Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, Imizu, Toyama, Japan.
  • Okon R; Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, Imizu, Toyama, Japan.
  • Nakagawa K; Laboratory of Hygienic Sciences, Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Chuo-ku, Kobe, Japan.
  • Tsugawa N; Department of Health and Nutrition, Faculty of Health and Nutrition, Osaka Shoin Women's University, Higashi-Osaka, Japan.
  • Okano T; Department of Hygienic Sciences, Kobe Pharmaceutical University, Higashinada-ku, Kobe, Japan.
  • Kawagoe F; Faculty of Pharmaceutical Sciences, Teikyo University, Tokyo, Japan.
  • Kittaka A; Faculty of Pharmaceutical Sciences, Teikyo University, Tokyo, Japan.
  • Ikushiro S; Department of Biotechnology, Faculty of Engineering, Toyama Prefectural University, Imizu, Toyama, Japan.
  • Sakaki T; Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, Imizu, Toyama, Japan. Electronic address: tsakaki@pu-toyama.ac.jp.
J Biol Chem ; 296: 100668, 2021.
Article em En | MEDLINE | ID: mdl-33865853
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vitaminas / Calcifediol / Citocromo P-450 CYP3A / Metaboloma / Sistemas CRISPR-Cas / Vitamina D3 24-Hidroxilase Limite: Animals Idioma: En Revista: J Biol Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vitaminas / Calcifediol / Citocromo P-450 CYP3A / Metaboloma / Sistemas CRISPR-Cas / Vitamina D3 24-Hidroxilase Limite: Animals Idioma: En Revista: J Biol Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão