Dysregulated Immunological Functionome and Dysfunctional Metabolic Pathway Recognized for the Pathogenesis of Borderline Ovarian Tumors by Integrative Polygenic Analytics.

Chang, Chia-Ming; Li, Yao-Feng; Lin, Hsin-Chung; Lu, Kai-Hsi; Lin, Tzu-Wei; Liu, Li-Chun; Su, Kuo-Min; Chang, Cheng-Chang

Chang, Chia-Ming; Li, Yao-Feng; Lin, Hsin-Chung; Lu, Kai-Hsi; Lin, Tzu-Wei; Liu, Li-Chun; Su, Kuo-Min; Chang, Cheng-Chang.

Afiliação

Chang CM; School of Medicine, National Yang-Ming University, Taipei 112, Taiwan.
Li YF; Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Lin HC; School of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Lu KH; Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.
Lin TW; Division of Clinical Pathology, Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.
Liu LC; Graduate Institute of Pathology and Parasitology, National Defense Medical Center, Taipei 114, Taiwan.
Su KM; Department of Medical Research and Education, Cheng-Hsin General Hospital, Taipei 112, Taiwan.
Chang CC; Department of Medical Research, Taipei Veterans General Hospital, Taipei 112, Taiwan.

Int J Mol Sci ; 22(8)2021 Apr 15.

Article em En | MEDLINE | ID: mdl-33921111

Assuntos

Redes e Vias Metabólicas; Herança Multifatorial/genética; Neoplasias Ovarianas/imunologia; Neoplasias Ovarianas/metabolismo; Feminino; Regulação Neoplásica da Expressão Gênica; Ontologia Genética; Humanos; Inflamação/patologia; Interleucina-6/metabolismo; Aprendizado de Máquina; Neoplasias Ovarianas/genética; Reprodutibilidade dos Testes; Transdução de Sinais/genética; Transcriptoma; UTP-Hexose-1-Fosfato Uridililtransferase/metabolismo

Palavras-chave

borderline ovarian tumors (BOTs); cell cycle and signaling; cell membrane and transporter; cell metabolism; functionome-based and data-driven analysis; galactose catabolism; gene ontology (GO); immune and inflammatory response

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Herança Multifatorial / Redes e Vias Metabólicas Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Female / Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Taiwan

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