Tumour Hypoxia-Mediated Immunosuppression: Mechanisms and Therapeutic Approaches to Improve Cancer Immunotherapy.

Fu, Zhe; Mowday, Alexandra M; Smaill, Jeff B; Hermans, Ian F; Patterson, Adam V

Fu, Zhe; Mowday, Alexandra M; Smaill, Jeff B; Hermans, Ian F; Patterson, Adam V.

Afiliação

Fu Z; Malaghan Institute of Medical Research, Wellington 6042, New Zealand.
Mowday AM; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, University of Auckland, Auckland 1142, New Zealand.
Smaill JB; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, University of Auckland, Auckland 1142, New Zealand.
Hermans IF; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Auckland 1142, New Zealand.
Patterson AV; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, University of Auckland, Auckland 1142, New Zealand.

Cells ; 10(5)2021 04 24.

Article em En | MEDLINE | ID: mdl-33923305

Assuntos

Imunidade/imunologia; Terapia de Imunossupressão/métodos; Imunoterapia/métodos; Terapia de Alvo Molecular/métodos; Neoplasias/terapia; Microambiente Tumoral; Animais; Humanos; Neoplasias/imunologia; Neoplasias/patologia

Palavras-chave

CP-506; HIF; checkpoint inhibitor; evofosfamide; hypoxia; hypoxia-activated prodrug; immune suppression; immunotherapy; oncolytic virus; tarloxotinib

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terapia de Imunossupressão / Terapia de Alvo Molecular / Microambiente Tumoral / Imunidade / Imunoterapia / Neoplasias Limite: Animals / Humans Idioma: En Revista: Cells Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Nova Zelândia

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