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Cell-free DNA captures tumor heterogeneity and driver alterations in rapid autopsies with pre-treated metastatic cancer.
Pereira, Bernard; Chen, Christopher T; Goyal, Lipika; Walmsley, Charlotte; Pinto, Christopher J; Baiev, Islam; Allen, Read; Henderson, Laura; Saha, Supriya; Reyes, Stephanie; Taylor, Martin S; Fitzgerald, Donna M; Broudo, Maida Williams; Sahu, Avinash; Gao, Xin; Winckler, Wendy; Brannon, A Rose; Engelman, Jeffrey A; Leary, Rebecca; Stone, James R; Campbell, Catarina D; Juric, Dejan.
Afiliação
  • Pereira B; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Chen CT; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Goyal L; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Walmsley C; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Pinto CJ; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Baiev I; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Allen R; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Henderson L; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Saha S; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Reyes S; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Taylor MS; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA.
  • Fitzgerald DM; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Broudo MW; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Sahu A; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Gao X; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Winckler W; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Brannon AR; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Engelman JA; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Leary R; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Stone JR; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA.
  • Campbell CD; Novartis Institutes for Biomedical Research, Cambridge, MA, USA. Katie.Campbell@novartis.com.
  • Juric D; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA. Juric.Dejan@mgh.harvard.edu.
Nat Commun ; 12(1): 3199, 2021 05 27.
Article em En | MEDLINE | ID: mdl-34045463
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autopsia / Análise Mutacional de DNA / Microambiente Tumoral / DNA Tumoral Circulante / Neoplasias Tipo de estudo: Diagnostic_studies / Etiology_studies / Evaluation_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autopsia / Análise Mutacional de DNA / Microambiente Tumoral / DNA Tumoral Circulante / Neoplasias Tipo de estudo: Diagnostic_studies / Etiology_studies / Evaluation_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos