Amide-Amine Replacement in Indole-2-carboxamides Yields Potent Mycobactericidal Agents with Improved Water Solubility.

Tan, Yu Jia; Li, Ming; Gunawan, Gregory Adrian; Nyantakyi, Samuel Agyei; Dick, Thomas; Go, Mei-Lin; Lam, Yulin

Tan, Yu Jia; Li, Ming; Gunawan, Gregory Adrian; Nyantakyi, Samuel Agyei; Dick, Thomas; Go, Mei-Lin; Lam, Yulin.

Afiliação

Tan YJ; Department of Chemistry and Department of Pharmacy, National University of Singapore, 117543 Singapore.
Li M; Department of Chemistry and Department of Pharmacy, National University of Singapore, 117543 Singapore.
Gunawan GA; Department of Chemistry and Department of Pharmacy, National University of Singapore, 117543 Singapore.
Nyantakyi SA; Department of Chemistry and Department of Pharmacy, National University of Singapore, 117543 Singapore.
Dick T; Center for Discovery and Innovation, Hackensack Meridian Health, and Department of Medical Sciences, Hackensack Meridian School of Medicine, Nutley, New Jersey 07110, United States.
Go ML; Department of Microbiology and Immunology, Georgetown University, Washington, D.C. 20057, United States.
Lam Y; Department of Chemistry and Department of Pharmacy, National University of Singapore, 117543 Singapore.

ACS Med Chem Lett ; 12(5): 704-712, 2021 May 13.

Article em En | MEDLINE | ID: mdl-34055215

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2021 Tipo de documento: Article