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Mechanistic physiology-based pharmacokinetic modeling to elucidate vincristine-induced peripheral neuropathy following treatment with novel kinase inhibitors.
Pilla Reddy, Venkatesh; Fretland, Adrian J; Zhou, Diansong; Sharma, Shringi; Chen, Buyun; Vishwanathan, Karthick; McGinnity, Dermot F; Xu, Yan; Ware, Joseph A.
Afiliação
  • Pilla Reddy V; Early Oncology, Oncology Research & Development, AstraZeneca, Cambridge, UK. Venkatesh.Reddy@astrazeneca.com.
  • Fretland AJ; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, Biopharmaceuticals Research & Development, AstraZeneca, Cambridge, UK. Venkatesh.Reddy@astrazeneca.com.
  • Zhou D; Early Oncology, Oncology Research & Development, AstraZeneca, Boston, MA, USA.
  • Sharma S; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, Biopharmaceuticals Research & Development, AstraZeneca, Boston, MA, USA.
  • Chen B; Quantitative Clinical Pharmacology, AstraZeneca , South San Francisco, CA, USA.
  • Vishwanathan K; Quantitative Clinical Pharmacology, AstraZeneca , South San Francisco, CA, USA.
  • McGinnity DF; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, Biopharmaceuticals Research & Development, AstraZeneca, Boston, MA, USA.
  • Xu Y; Early Oncology, Oncology Research & Development, AstraZeneca, Cambridge, UK.
  • Ware JA; Quantitative Clinical Pharmacology, AstraZeneca , South San Francisco, CA, USA.
Cancer Chemother Pharmacol ; 88(3): 451-464, 2021 09.
Article em En | MEDLINE | ID: mdl-34080039
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vincristina / Protocolos de Quimioterapia Combinada Antineoplásica / Doenças do Sistema Nervoso Periférico / Modelos Biológicos Tipo de estudo: Prognostic_studies Limite: Aged80 Idioma: En Revista: Cancer Chemother Pharmacol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vincristina / Protocolos de Quimioterapia Combinada Antineoplásica / Doenças do Sistema Nervoso Periférico / Modelos Biológicos Tipo de estudo: Prognostic_studies Limite: Aged80 Idioma: En Revista: Cancer Chemother Pharmacol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido