Selective inhibition of the K<sup>+</sup> efflux sensitive NLRP3 pathway by Cl<sup>-</sup> channel modulation.

Swanton, Tessa; Beswick, James A; Hammadi, Halah; Morris, Lucy; Williams, Daniel; de Cesco, Stephane; El-Sharkawy, Lina; Yu, Shi; Green, Jack; Davis, John B; Lawrence, Catherine B; Brough, David; Freeman, Sally

Selective inhibition of the K⁺ efflux sensitive NLRP3 pathway by Cl^- channel modulation.

Swanton, Tessa; Beswick, James A; Hammadi, Halah; Morris, Lucy; Williams, Daniel; de Cesco, Stephane; El-Sharkawy, Lina; Yu, Shi; Green, Jack; Davis, John B; Lawrence, Catherine B; Brough, David; Freeman, Sally.

Afiliação

Swanton T; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester AV Hill Building, Oxford Road Manchester M13 9PT UK David.brough@manchester.ac.uk.
Beswick JA; Lydia Becker Institute of Immunology and Inflammation, University of Manchester Manchester M13 9PT UK.
Hammadi H; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester Stopford Building, Oxford Road Manchester M13 9PT UK Sally.freeman@manchester.ac.uk.
Morris L; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester Stopford Building, Oxford Road Manchester M13 9PT UK Sally.freeman@manchester.ac.uk.
Williams D; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester AV Hill Building, Oxford Road Manchester M13 9PT UK David.brough@manchester.ac.uk.
de Cesco S; Lydia Becker Institute of Immunology and Inflammation, University of Manchester Manchester M13 9PT UK.
El-Sharkawy L; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester AV Hill Building, Oxford Road Manchester M13 9PT UK David.brough@manchester.ac.uk.
Yu S; Lydia Becker Institute of Immunology and Inflammation, University of Manchester Manchester M13 9PT UK.
Green J; Alzheimer's Research UK Oxford Drug Discovery Institute, Target Discovery Institute NDM Building, Roosevelt Drive Oxford OX3 7FZ UK.
Davis JB; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester Stopford Building, Oxford Road Manchester M13 9PT UK Sally.freeman@manchester.ac.uk.
Lawrence CB; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester AV Hill Building, Oxford Road Manchester M13 9PT UK David.brough@manchester.ac.uk.
Brough D; Lydia Becker Institute of Immunology and Inflammation, University of Manchester Manchester M13 9PT UK.
Freeman S; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester AV Hill Building, Oxford Road Manchester M13 9PT UK David.brough@manchester.ac.uk.

Chem Sci ; 11(43): 11720-11728, 2020 Oct 12.

Article em En | MEDLINE | ID: mdl-34094411

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Revista: Chem Sci Ano de publicação: 2020 Tipo de documento: Article

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