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HTS-based discovery and optimization of novel positive allosteric modulators of the α7 nicotinic acetylcholine receptor.
Ledneczki, István; Horváth, Anita; Tapolcsányi, Pál; Éles, János; Molnár, Katalin Dudás; Vágó, István; Visegrády, András; Kiss, László; Szigetvári, Áron; Kóti, János; Krámos, Balázs; Mahó, Sándor; Holm, Patrik; Kolok, Sándor; Fodor, László; Thán, Márta; Kostyalik, Diána; Balázs, Ottilia; Vastag, Mónika; Greiner, István; Lévay, György; Lendvai, Balázs; Némethy, Zsolt.
Afiliação
  • Ledneczki I; Department of Chemistry, Gedeon Richter Plc., Budapest, Hungary. Electronic address: ledneczki@richter.hu.
  • Horváth A; Department of Chemistry, Gedeon Richter Plc., Budapest, Hungary.
  • Tapolcsányi P; Department of Chemistry, Gedeon Richter Plc., Budapest, Hungary.
  • Éles J; Department of Chemistry, Gedeon Richter Plc., Budapest, Hungary.
  • Molnár KD; Department of Chemistry, Gedeon Richter Plc., Budapest, Hungary.
  • Vágó I; Department of Chemistry, Gedeon Richter Plc., Budapest, Hungary.
  • Visegrády A; Pharmacological and Drug Safety Research, Gedeon Richter Plc., Budapest, Hungary.
  • Kiss L; Pharmacological and Drug Safety Research, Gedeon Richter Plc., Budapest, Hungary.
  • Szigetvári Á; Spectroscopic Research Department, Gedeon Richter Plc., Budapest, Hungary.
  • Kóti J; Spectroscopic Research Department, Gedeon Richter Plc., Budapest, Hungary.
  • Krámos B; Spectroscopic Research Department, Gedeon Richter Plc., Budapest, Hungary.
  • Mahó S; Department of Chemistry, Gedeon Richter Plc., Budapest, Hungary.
  • Holm P; Orion Corporation, Turku, Finland.
  • Kolok S; Pharmacological and Drug Safety Research, Gedeon Richter Plc., Budapest, Hungary.
  • Fodor L; Pharmacological and Drug Safety Research, Gedeon Richter Plc., Budapest, Hungary.
  • Thán M; Pharmacological and Drug Safety Research, Gedeon Richter Plc., Budapest, Hungary.
  • Kostyalik D; Pharmacological and Drug Safety Research, Gedeon Richter Plc., Budapest, Hungary.
  • Balázs O; Pharmacological and Drug Safety Research, Gedeon Richter Plc., Budapest, Hungary.
  • Vastag M; Pharmacological and Drug Safety Research, Gedeon Richter Plc., Budapest, Hungary.
  • Greiner I; Research Management, Gedeon Richter Plc., Budapest, Hungary.
  • Lévay G; Pharmacological and Drug Safety Research, Gedeon Richter Plc., Budapest, Hungary.
  • Lendvai B; Pharmacological and Drug Safety Research, Gedeon Richter Plc., Budapest, Hungary.
  • Némethy Z; Pharmacological and Drug Safety Research, Gedeon Richter Plc., Budapest, Hungary.
Eur J Med Chem ; 222: 113560, 2021 Oct 15.
Article em En | MEDLINE | ID: mdl-34111828
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Oxálico / Descoberta de Drogas / Ensaios de Triagem em Larga Escala / Receptor Nicotínico de Acetilcolina alfa7 / Amidas Limite: Animals / Humans / Male Idioma: En Revista: Eur J Med Chem Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Oxálico / Descoberta de Drogas / Ensaios de Triagem em Larga Escala / Receptor Nicotínico de Acetilcolina alfa7 / Amidas Limite: Animals / Humans / Male Idioma: En Revista: Eur J Med Chem Ano de publicação: 2021 Tipo de documento: Article