Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-<i>&#954;</i>B, MKK7/JNK, and JAK2/STAT1 Signalling Pathways.

Lee, Nami; Heo, Yu Jung; Choi, Sung-E; Jeon, Ja Young; Han, Seung Jin; Kim, Dae Jung; Kang, Yup; Lee, Kwan Woo; Kim, Hae Jin

Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-κB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways.

Lee, Nami; Heo, Yu Jung; Choi, Sung-E; Jeon, Ja Young; Han, Seung Jin; Kim, Dae Jung; Kang, Yup; Lee, Kwan Woo; Kim, Hae Jin.

Afiliação

Lee N; Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Republic of Korea.
Heo YJ; Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Republic of Korea.
Choi SE; Department of Physiology, Ajou University School of medicine, Suwon, Republic of Korea.
Jeon JY; Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Republic of Korea.
Han SJ; Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Republic of Korea.
Kim DJ; Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Republic of Korea.
Kang Y; Department of Physiology, Ajou University School of medicine, Suwon, Republic of Korea.
Lee KW; Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Republic of Korea.
Kim HJ; Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Republic of Korea.

J Immunol Res ; 2021: 9944880, 2021.

Article em En | MEDLINE | ID: mdl-34124273

Assuntos

Anti-Inflamatórios/farmacologia; Compostos Benzidrílicos/farmacologia; Inibidores da Dipeptidil Peptidase IV/farmacologia; Glucosídeos/farmacologia; Macrófagos/imunologia; Piperidonas/farmacologia; Pirimidinas/farmacologia; Inibidores do Transportador 2 de Sódio-Glicose/farmacologia; Animais; Quinase I-kappa B/metabolismo; Janus Quinase 2/metabolismo; Lipopolissacarídeos/imunologia; MAP Quinase Quinase 4/metabolismo; MAP Quinase Quinase 7/metabolismo; Ativação de Macrófagos/efeitos dos fármacos; Camundongos; NF-kappa B/metabolismo; Células RAW 264.7; Fator de Transcrição STAT1/metabolismo; Transdução de Sinais

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperidonas / Pirimidinas / Compostos Benzidrílicos / Inibidores da Dipeptidil Peptidase IV / Inibidores do Transportador 2 de Sódio-Glicose / Glucosídeos / Macrófagos / Anti-Inflamatórios Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Immunol Res Ano de publicação: 2021 Tipo de documento: Article

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