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High tumour mutational burden and EGFR/MAPK pathway activation are therapeutic targets in metastatic porocarcinoma.
Westphal, D; Garzarolli, M; Sergon, M; Horak, P; Hutter, B; Becker, J C; Wiegel, M; Maczey, E; Blum, S; Grosche-Schlee, S; Rütten, A; Ugurel, S; Stenzinger, A; Glimm, H; Aust, D; Baretton, G; Beissert, S; Fröhling, S; Redler, S; Surowy, H; Meier, F.
Afiliação
  • Westphal D; Department of Dermatology, University Hospital Carl Gustav Carus at Technische Universität (TU) Dresden, Dresden, Germany.
  • Garzarolli M; National Center for Tumor Diseases (NCT), Dresden, Germany: German Cancer Research Center (DKFZ), Heidelberg, Germany; Faculty of Medicine and University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany; and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.
  • Sergon M; Department of Dermatology, University Hospital Carl Gustav Carus at Technische Universität (TU) Dresden, Dresden, Germany.
  • Horak P; Institute of Pathology, University Hospital Carl Gustav Carus at TU Dresden, Dresden, Germany.
  • Hutter B; German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Becker JC; Division of Translational Medical Oncology, National Center for Tumor Diseases (NCT) Heidelberg and DKFZ, Heidelberg, Germany.
  • Wiegel M; German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Maczey E; Computational Oncology, Molecular Diagnostics Program, NCT Heidelberg and DKFZ, Heidelberg, Germany.
  • Blum S; Division of Applied Bioinformatics, DKFZ, Heidelberg, Germany.
  • Grosche-Schlee S; Department of Dermatology, University Hospital Essen, Essen, Germany.
  • Rütten A; Translational Skin Cancer Research, DKTK, Partner Site Essen, Essen, Germany.
  • Ugurel S; Department of Dermatology, University Hospital Carl Gustav Carus at Technische Universität (TU) Dresden, Dresden, Germany.
  • Stenzinger A; Department of Dermatology, University Medical Center Tübingen, Tübingen, Germany.
  • Glimm H; Institute and Policlinic of Diagnostic and Interventional Radiology, University Hospital Carl Gustav Carus at TU Dresden, Dresden, Germany.
  • Aust D; Clinic and Policlinic of Nuclear Medicine, University Hospital Carl Gustav Carus at TU Dresden, Dresden, Germany.
  • Baretton G; Dermatopathology Friedrichshafen, Friedrichshafen, Germany.
  • Beissert S; Department of Dermatology, University Hospital Essen, Essen, Germany.
  • Fröhling S; German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Redler S; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
  • Surowy H; Translational Functional Cancer Genomics, NCT Heidelberg and DKFZ, Heidelberg, Germany.
  • Meier F; Department of Translational Medical Oncology NCT Dresden and DKFZ, Dresden, Germany.
Br J Dermatol ; 185(6): 1186-1199, 2021 12.
Article em En | MEDLINE | ID: mdl-34185311

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 6_skin_diseases Assunto principal: Neoplasias das Glândulas Sudoríparas / Sistema de Sinalização das MAP Quinases / Porocarcinoma Écrino / Receptores ErbB Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Br J Dermatol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 6_skin_diseases Assunto principal: Neoplasias das Glândulas Sudoríparas / Sistema de Sinalização das MAP Quinases / Porocarcinoma Écrino / Receptores ErbB Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Br J Dermatol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha
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