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Multi-omics profiling of a CHO cell culture system unravels the effect of culture pH on cell growth, antibody titer, and product quality.
Lee, Alison P; Kok, Yee Jiun; Lakshmanan, Meiyappan; Leong, Dawn; Zheng, Lu; Lim, Hsueh Lee; Chen, Shuwen; Mak, Shi Ya; Ang, Kok Siong; Templeton, Neil; Salim, Taha; Wei, Xiaona; Gifford, Eric; Tan, Andy Hee-Meng; Bi, Xuezhi; Ng, Say Kong; Lee, Dong-Yup; Ling, Wai Lam W; Ho, Ying Swan.
Afiliação
  • Lee AP; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Kok YJ; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Lakshmanan M; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Leong D; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Zheng L; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Lim HL; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Chen S; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Mak SY; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Ang KS; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Templeton N; Process Research and Development, Merck & Co. Inc., West Point, Pennsylvania, USA.
  • Salim T; Process Research and Development, Merck & Co. Inc., Kenilworth, New Jersey, USA.
  • Wei X; Scientific Informatics, MSD International GmbH (Singapore Branch), Singapore, Singapore.
  • Gifford E; Scientific Informatics, MSD International GmbH (Singapore Branch), Singapore, Singapore.
  • Tan AH; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Bi X; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Ng SK; Duke-NUS Medical School, Singapore, Singapore.
  • Lee DY; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Ling WLW; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Ho YS; School of Chemical Engineering, Sungkyunkwan University, Seoul, Gyeonggi-do, Republic of Korea.
Biotechnol Bioeng ; 118(11): 4305-4316, 2021 11.
Article em En | MEDLINE | ID: mdl-34289087

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxigênio / Ciclo Celular / Técnicas de Cultura de Células / Metabolômica / Anticorpos Monoclonais Limite: Animals Idioma: En Revista: Biotechnol Bioeng Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Singapura

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxigênio / Ciclo Celular / Técnicas de Cultura de Células / Metabolômica / Anticorpos Monoclonais Limite: Animals Idioma: En Revista: Biotechnol Bioeng Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Singapura
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