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TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma.
Seong, Bo Kyung A; Dharia, Neekesh V; Lin, Shan; Donovan, Katherine A; Chong, Shasha; Robichaud, Amanda; Conway, Amy; Hamze, Amanda; Ross, Linda; Alexe, Gabriela; Adane, Biniam; Nabet, Behnam; Ferguson, Fleur M; Stolte, Björn; Wang, Emily Jue; Sun, Jialin; Darzacq, Xavier; Piccioni, Federica; Gray, Nathanael S; Fischer, Eric S; Stegmaier, Kimberly.
Afiliação
  • Seong BKA; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Dharia NV; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA; The Broad Institute of MIT and Harvard, Cambridge, MA, USA; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.
  • Lin S; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Donovan KA; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Chong S; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA; Howard Hughes Medical Institute, University of California, Berkeley, CA, USA.
  • Robichaud A; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Conway A; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Hamze A; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Ross L; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Alexe G; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Adane B; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Nabet B; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Ferguson FM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Stolte B; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA; Dr.von Hauner Children's Hospital, Department of Pediatrics, University Hospital, LMU Munich, Munich, Germany.
  • Wang EJ; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Sun J; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Darzacq X; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA; CIRM Center of Excellence, University of California, Berkeley, CA, USA.
  • Piccioni F; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Gray NS; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Fischer ES; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Stegmaier K; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA; The Broad Institute of MIT and Harvard, Cambridge, MA, USA; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA. Electronic address: kimberly_stegmaier@dfci.harvard.edu.
Cancer Cell ; 39(9): 1262-1278.e7, 2021 09 13.
Article em En | MEDLINE | ID: mdl-34329586
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 6_other_malignant_neoplasms Assunto principal: Sarcoma de Ewing / Neoplasias Ósseas / Proteínas de Transporte / Proteínas de Fusão Oncogênica / Proteína EWS de Ligação a RNA / Proteína Proto-Oncogênica c-fli-1 / Proteínas do Tecido Nervoso Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cancer Cell Assunto da revista: NEOPLASIAS Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 6_other_malignant_neoplasms Assunto principal: Sarcoma de Ewing / Neoplasias Ósseas / Proteínas de Transporte / Proteínas de Fusão Oncogênica / Proteína EWS de Ligação a RNA / Proteína Proto-Oncogênica c-fli-1 / Proteínas do Tecido Nervoso Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cancer Cell Assunto da revista: NEOPLASIAS Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos