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PIKE-A promotes glioblastoma growth by driving PPP flux through increasing G6PD expression mediated by phosphorylation of STAT3.
Sun, Mingming; Sheng, Hao; Wu, Tingfeng; Song, Jiaqi; Sun, Huanran; Wang, Yingzhi; Wang, Jiyan; Li, Zhen; Zhao, Huifang; Tan, Junzhen; Li, Yanping; Chen, Guo; Huang, Qingrong; Zhang, Yuan; Lan, Bei; Liu, Shuangping; Shan, Changliang; Zhang, Shuai.
Afiliação
  • Sun M; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China.
  • Sheng H; Biomedical Translational Research Institute, Jinan University, Guangzhou, Guangdong 510632, China.
  • Wu T; Department of Neurosurgery, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong 510632, China.
  • Song J; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China.
  • Sun H; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China.
  • Wang Y; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China.
  • Wang J; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China.
  • Li Z; Biomedical Translational Research Institute, Jinan University, Guangzhou, Guangdong 510632, China.
  • Zhao H; School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
  • Tan J; School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
  • Li Y; Department of Pathology and Institute of Precision Medicine, Jining Medical University, Jining, Shandong 272067, China.
  • Chen G; Department of Medical Biochemistry and Molecular Biology, School of Medicine, Jinan University, Guangzhou 510632, China.
  • Huang Q; School of Life Sciences, Ludong University, Yantai, Shandong 264025, China.
  • Zhang Y; Qingyuan People's Hospital, Qingyuan, Guangdong 511518, China.
  • Lan B; Department of Biochemistry and Molecular Biology, Tianjin Medical University, Tianjin 300070, China.
  • Liu S; Department of Pathology, Medical School, Dalian University, Dalian, Liaoning 116622, China. Electronic address: liushuangping@dlu.edu.cn.
  • Shan C; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China. Electronic address: changliangshan@nankai.edu.cn.
  • Zhang S; School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China. Electronic address: shuaizhang@tjutcm.edu.cn.
Biochem Pharmacol ; 192: 114736, 2021 10.
Article em En | MEDLINE | ID: mdl-34411567
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Via de Pentose Fosfato / Glioblastoma / Proteínas de Ligação ao GTP / Proteínas Ativadoras de GTPase / Proliferação de Células / Fator de Transcrição STAT3 / Glucosefosfato Desidrogenase Limite: Animals / Humans / Male Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Via de Pentose Fosfato / Glioblastoma / Proteínas de Ligação ao GTP / Proteínas Ativadoras de GTPase / Proliferação de Células / Fator de Transcrição STAT3 / Glucosefosfato Desidrogenase Limite: Animals / Humans / Male Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China