Limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) is independently associated with dementia and strongly associated with arteriolosclerosis in the oldest-old.

Harrison, William T; Lusk, Jay B; Liu, Beiyu; Ervin, John F; Johnson, Kim G; Green, Cynthia L; Wang, Shih-Hsiu J

Harrison, William T; Lusk, Jay B; Liu, Beiyu; Ervin, John F; Johnson, Kim G; Green, Cynthia L; Wang, Shih-Hsiu J.

Afiliação

Harrison WT; Department of Pathology, Duke University Medical Center, 214MA Davison Bldg., 40 Duke Medicine Circle, Durham, NC, 27710, USA.
Lusk JB; Department of Pathology, Wake Forest School of Medicine, Winston-Salem, USA.
Liu B; Department of Pathology, Duke University Medical Center, 214MA Davison Bldg., 40 Duke Medicine Circle, Durham, NC, 27710, USA.
Ervin JF; Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, USA.
Johnson KG; Department of Neurology, Duke University Medical Center, Durham, USA.
Green CL; Department of Neurology, Duke University Medical Center, Durham, USA.
Wang SJ; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, USA.

Acta Neuropathol ; 142(5): 917-919, 2021 11.

Article em En | MEDLINE | ID: mdl-34415381

Assuntos

Arteriolosclerose/patologia; Demência/patologia; Lobo Límbico/patologia; Proteinopatias TDP-43/patologia; Idoso de 80 Anos ou mais; Feminino; Humanos; Masculino

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Demência / Arteriolosclerose / Proteinopatias TDP-43 / Lobo Límbico Tipo de estudo: Risk_factors_studies Limite: Aged80 / Female / Humans / Male Idioma: En Revista: Acta Neuropathol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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