Formulation development and in vitro-in vivo assessment of protransfersomal gel of anti-resorptive drug in osteoporosis treatment.

Gyanewali, Suman; Kesharwani, Prashant; Sheikh, Afsana; Ahmad, Farhan Jalees; Trivedi, Ritu; Talegaonkar, Sushama

Gyanewali, Suman; Kesharwani, Prashant; Sheikh, Afsana; Ahmad, Farhan Jalees; Trivedi, Ritu; Talegaonkar, Sushama.

Afiliação

Gyanewali S; Department of Pharmaceutics, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi 110062, India.
Kesharwani P; Department of Pharmaceutics, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi 110062, India. Electronic address: prashantdops@gmail.com.
Sheikh A; Department of Pharmaceutics, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi 110062, India.
Ahmad FJ; Department of Pharmaceutics, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi 110062, India.
Trivedi R; Department of Endocrinology, CSIR-Central Drug Research Institute, Lucknow, India.
Talegaonkar S; Department of Pharmaceutics, Delhi Pharmaceutical Sciences and Research University, New Delhi 110017, India. Electronic address: stalegaonkar@gmail.com.

Int J Pharm ; 608: 121060, 2021 Oct 25.

Article em En | MEDLINE | ID: mdl-34500057

Assuntos

Osteoporose; Absorção Cutânea; Administração Cutânea; Animais; Portadores de Fármacos/metabolismo; Sistemas de Liberação de Medicamentos; Humanos; Osteoporose/tratamento farmacológico; Osteoporose/metabolismo; Tamanho da Partícula; Ratos; Ratos Wistar; Pele/metabolismo

Palavras-chave

Alkaline phosphatase level; Bioavailability enhancement; Bone strength; Microcomputed tomography; Protransfersomes; Transdermal drug delivery

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 6_endocrine_disorders / 6_musculoskeletal_diseases_rheumatic_disorders Assunto principal: Osteoporose / Absorção Cutânea Limite: Animals / Humans Idioma: En Revista: Int J Pharm Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Índia

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