Antibody Deficiency, Chronic Lung Disease, and Comorbid Conditions: A Case-Based Approach.
J Allergy Clin Immunol Pract
; 9(11): 3899-3908, 2021 11.
Article
em En
| MEDLINE
| ID: mdl-34592394
ABSTRACT
New emerging pulmonary phenotypes associated with antibody deficiency, such as neutrophilic asthma, frequent exacerbations of chronic obstructive pulmonary disease, and unexplained interstitial lung disease, particularly in younger adults, are discussed in this review through a case-based approach. Also discussed in similar fashion are antibody deficiency syndromes that lead to end-stage lung disease and the indications for lung transplantation in primary immunodeficiency disease. These challenging cases require timely and individualized strategies for genetic and immunologic diagnosis, decisions about therapeutic approaches, and long-term monitoring.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Asma
/
Transplante de Pulmão
/
Doenças Pulmonares Intersticiais
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Doença Pulmonar Obstrutiva Crônica
/
Doenças da Imunodeficiência Primária
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
J Allergy Clin Immunol Pract
Ano de publicação:
2021
Tipo de documento:
Article