Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation.

White, Alex D; Peña, Karina A; Clark, Lisa J; Maria, Christian Santa; Liu, Shi; Jean-Alphonse, Frédéric G; Lee, Ji Young; Lei, Saifei; Cheng, Zhiqiang; Tu, Chia-Ling; Fang, Fei; Szeto, Nicholas; Gardella, Thomas J; Xiao, Kunhong; Gellman, Samuel H; Bahar, Ivet; Sutkeviciute, Ieva; Chang, Wenhan; Vilardaga, Jean-Pierre

White, Alex D; Peña, Karina A; Clark, Lisa J; Maria, Christian Santa; Liu, Shi; Jean-Alphonse, Frédéric G; Lee, Ji Young; Lei, Saifei; Cheng, Zhiqiang; Tu, Chia-Ling; Fang, Fei; Szeto, Nicholas; Gardella, Thomas J; Xiao, Kunhong; Gellman, Samuel H; Bahar, Ivet; Sutkeviciute, Ieva; Chang, Wenhan; Vilardaga, Jean-Pierre.

Afiliação

White AD; Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Peña KA; Graduate Program in Molecular Pharmacology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Clark LJ; Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Maria CS; Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Liu S; Graduate Program in Molecular Biology and Structural Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Jean-Alphonse FG; Endocrine Research Unit, Department of Veterans Affairs Medical Center, and University of California, San Francisco, CA 94158, USA.
Lee JY; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.
Lei S; Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Cheng Z; Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA.
Tu CL; Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Fang F; Endocrine Research Unit, Department of Veterans Affairs Medical Center, and University of California, San Francisco, CA 94158, USA.
Szeto N; Endocrine Research Unit, Department of Veterans Affairs Medical Center, and University of California, San Francisco, CA 94158, USA.
Gardella TJ; Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Xiao K; Endocrine Research Unit, Department of Veterans Affairs Medical Center, and University of California, San Francisco, CA 94158, USA.
Gellman SH; Endocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Bahar I; Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Sutkeviciute I; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.
Chang W; Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA.
Vilardaga JP; Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.

Sci Signal ; 14(703): eabc5944, 2021 Oct 05.

Article em En | MEDLINE | ID: mdl-34609896

Assuntos

Hormônio Paratireóideo; Receptores de Hormônios Paratireóideos; AMP Cíclico

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hormônio Paratireóideo / Receptores de Hormônios Paratireóideos Idioma: En Revista: Sci Signal Assunto da revista: CIENCIA / FISIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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