<sup>125</sup>I seeds inhibit proliferation and promote apoptosis in cholangiocarcinoma cells by regulating the AGR2-mediated p38 MAPK pathway.

Zhou, Xueliang; Zhang, Wenguang; Dou, Mengmeng; Li, Zhaonan; Liu, Zaoqu; Li, Jing; Tian, Chuan; Yao, Yuan; Wang, Chaoyan; Li, Yahua; Chen, Pengfei; Han, Xinwei; Jiao, Dechao

¹²⁵I seeds inhibit proliferation and promote apoptosis in cholangiocarcinoma cells by regulating the AGR2-mediated p38 MAPK pathway.

Zhou, Xueliang; Zhang, Wenguang; Dou, Mengmeng; Li, Zhaonan; Liu, Zaoqu; Li, Jing; Tian, Chuan; Yao, Yuan; Wang, Chaoyan; Li, Yahua; Chen, Pengfei; Han, Xinwei; Jiao, Dechao.

Afiliação

Zhou X; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhang W; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Dou M; Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Li Z; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Liu Z; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Li J; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Tian C; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yao Y; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Wang C; Department of Magnetic Resonance, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Li Y; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Chen P; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Han X; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. Electronic address: fcchanxw@zzu.edu.cn.
Jiao D; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. Electronic address: jiaodechao007@126.com.

Cancer Lett ; 524: 29-41, 2022 01 01.

Article em En | MEDLINE | ID: mdl-34656689

Assuntos

Colangiocarcinoma/radioterapia; Radioisótopos do Iodo/farmacologia; Mucoproteínas/genética; Proteínas Oncogênicas/genética; Proteínas Quinases p38 Ativadas por Mitógeno/genética; Animais; Apoptose/efeitos da radiação; Linhagem Celular Tumoral; Movimento Celular/efeitos da radiação; Proliferação de Células/efeitos da radiação; Colangiocarcinoma/genética; Colangiocarcinoma/patologia; Fosfatase 1 de Especificidade Dupla/genética; Regulação Neoplásica da Expressão Gênica/efeitos da radiação; Xenoenxertos; Humanos; Camundongos; Transdução de Sinais/efeitos da radiação; Proteína Supressora de Tumor p53/genética

Palavras-chave

(125)I seeds; AGR2; Apoptosis; Cholangiocarcinoma; p38 MAPK pathway

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Oncogênicas / Colangiocarcinoma / Proteínas Quinases p38 Ativadas por Mitógeno / Radioisótopos do Iodo / Mucoproteínas Limite: Animals / Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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