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Inability to switch from ARID1A-BAF to ARID1B-BAF impairs exit from pluripotency and commitment towards neural crest formation in ARID1B-related neurodevelopmental disorders.
Pagliaroli, Luca; Porazzi, Patrizia; Curtis, Alyxandra T; Scopa, Chiara; Mikkers, Harald M M; Freund, Christian; Daxinger, Lucia; Deliard, Sandra; Welsh, Sarah A; Offley, Sarah; Ott, Connor A; Calabretta, Bruno; Brugmann, Samantha A; Santen, Gijs W E; Trizzino, Marco.
Afiliação
  • Pagliaroli L; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
  • Porazzi P; Department of Cancer Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
  • Curtis AT; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
  • Scopa C; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
  • Mikkers HMM; Department of Cell & Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.
  • Freund C; LUMC hiPSC Hotel, Dept. Anatomy & Embryology, Leiden University Medical Center, Leiden, The Netherlands.
  • Daxinger L; Department of Human Genetics, Leiden University Medical Center (LUMC), Leiden, 2300, RC, The Netherlands.
  • Deliard S; Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, PA, USA.
  • Welsh SA; Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, PA, USA.
  • Offley S; Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, PA, USA.
  • Ott CA; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
  • Calabretta B; Department of Cancer Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
  • Brugmann SA; Divisions of Developmental Biology and Plastic Surgery, Department of Pediatrics at Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Santen GWE; Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.
  • Trizzino M; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA. marco.trizzino@jefferson.edu.
Nat Commun ; 12(1): 6469, 2021 11 09.
Article em En | MEDLINE | ID: mdl-34753942
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Cromatina / Proteínas de Ligação a DNA / Proteína Homeobox Nanog / Crista Neural Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Cromatina / Proteínas de Ligação a DNA / Proteína Homeobox Nanog / Crista Neural Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos