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Children with atopic dermatitis show increased activity of ß-glucocerebrosidase and stratum corneum levels of glucosylcholesterol that are strongly related to the local cytokine milieu.
Kezic, Sanja; McAleer, Maeve A; Jakasa, Ivone; Goorden, Susan M I; der Vlugt, Karen Ghauharali-van; Beers-Stet, Femke S; Meijer, Judith; Roelofsen, Jeroen; Nieman, Monique M; van Kuilenburg, André B P; Irvine, Alan D.
Afiliação
  • Kezic S; Amsterdam UMC, University of Amsterdam, Department of Public and Occupational Health, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.
  • McAleer MA; Clinical Medicine, Trinity College Dublin, Dublin, Ireland.
  • Jakasa I; Paediatric Dermatology, Children's Health Ireland at Crumlin, Dublin, 12, Ireland.
  • Goorden SMI; Laboratory for Analytical Chemistry, Department of Chemistry and Biochemistry, Faculty of Food Technology and Biotechnology, University of Zagreb, Zagreb, Croatia.
  • der Vlugt KG; Amsterdam UMC, University of Amsterdam, Laboratory Genetic Metabolic Diseases, Department of Clinical Chemistry, Amsterdam, the Netherlands.
  • Beers-Stet FS; Amsterdam UMC, University of Amsterdam, Laboratory Genetic Metabolic Diseases, Department of Clinical Chemistry, Amsterdam, the Netherlands.
  • Meijer J; Amsterdam UMC, University of Amsterdam, Laboratory Genetic Metabolic Diseases, Department of Clinical Chemistry, Amsterdam, the Netherlands.
  • Roelofsen J; Amsterdam UMC, University of Amsterdam, Laboratory Genetic Metabolic Diseases, Department of Clinical Chemistry, Amsterdam, the Netherlands.
  • Nieman MM; Amsterdam UMC, University of Amsterdam, Laboratory Genetic Metabolic Diseases, Department of Clinical Chemistry, Amsterdam, the Netherlands.
  • van Kuilenburg ABP; Amsterdam UMC, University of Amsterdam, Laboratory Genetic Metabolic Diseases, Department of Clinical Chemistry, Amsterdam, the Netherlands.
  • Irvine AD; Amsterdam UMC, University of Amsterdam, Laboratory Genetic Metabolic Diseases, Department of Clinical Chemistry, Amsterdam, the Netherlands.
Br J Dermatol ; 186(6): 988-996, 2022 06.
Article em En | MEDLINE | ID: mdl-34993951

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dermatite Atópica / Glucosilceramidase Limite: Child / Humans / Infant Idioma: En Revista: Br J Dermatol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dermatite Atópica / Glucosilceramidase Limite: Child / Humans / Infant Idioma: En Revista: Br J Dermatol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda
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