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CD74 ablation rescues type 2 diabetes mellitus-induced cardiac remodeling and contractile dysfunction through pyroptosis-evoked regulation of ferroptosis.
Chen, Lin; Yin, Zhiqiang; Qin, Xing; Zhu, Xiaoying; Chen, Xu; Ding, Gangbing; Sun, Dong; Wu, Ne N; Fei, Juanjuan; Bi, Yaguang; Zhang, Jingjing; Bucala, Richard; Ren, Jun; Zheng, Qijun.
Afiliação
  • Chen L; Department of Cardiovascular Surgery, Shenzhen People's Hospital, Shenzhen 518020, Guangdong, China; The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology, Shenzhen 518020, Guangdong, China.
  • Yin Z; Department of Cardiovascular Surgery, Shenzhen People's Hospital, Shenzhen 518020, Guangdong, China; The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology, Shenzhen 518020, Guangdong, China.
  • Qin X; Department of Cardiology, Xijing Hospital, The Air Force Military Medical University, Xi'an 710032 China.
  • Zhu X; Department of Cardiovascular Surgery, Shenzhen People's Hospital, Shenzhen 518020, Guangdong, China; The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology, Shenzhen 518020, Guangdong, China.
  • Chen X; Department of Cardiovascular Surgery, Shenzhen People's Hospital, Shenzhen 518020, Guangdong, China; The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology, Shenzhen 518020, Guangdong, China.
  • Ding G; Department of Cardiovascular Surgery, Shenzhen People's Hospital, Shenzhen 518020, Guangdong, China; The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology, Shenzhen 518020, Guangdong, China.
  • Sun D; Department of Cardiology, Xijing Hospital, The Air Force Military Medical University, Xi'an 710032 China.
  • Wu NN; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
  • Fei J; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
  • Bi Y; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
  • Zhang J; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, Key Laboratory of Diabetes Immunology, Ministry of Education, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha 410011, Hunan, China.
  • Bucala R; Department of Medicine, Yale School of Medicine, New Haven, CT 06520 USA.
  • Ren J; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China; Department of Laboratory Medicine and Pathology, University of Washington, Seattle 98195, WA, USA. Electronic address: jren@uw.edu.
  • Zheng Q; Department of Cardiovascular Surgery, Shenzhen People's Hospital, Shenzhen 518020, Guangdong, China; The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology, Shenzhen 518020, Guangdong, China. Electronic address: zhengqj@szh
Pharmacol Res ; 176: 106086, 2022 02.
Article em En | MEDLINE | ID: mdl-35033649
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antígenos de Diferenciação de Linfócitos B / Antígenos de Histocompatibilidade Classe II / Remodelação Ventricular / Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 2 / Piroptose / Ferroptose Limite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antígenos de Diferenciação de Linfócitos B / Antígenos de Histocompatibilidade Classe II / Remodelação Ventricular / Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 2 / Piroptose / Ferroptose Limite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China