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Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern.
Wratil, Paul R; Stern, Marcel; Priller, Alina; Willmann, Annika; Almanzar, Giovanni; Vogel, Emanuel; Feuerherd, Martin; Cheng, Cho-Chin; Yazici, Sarah; Christa, Catharina; Jeske, Samuel; Lupoli, Gaia; Vogt, Tim; Albanese, Manuel; Mejías-Pérez, Ernesto; Bauernfried, Stefan; Graf, Natalia; Mijocevic, Hrvoje; Vu, Martin; Tinnefeld, Kathrin; Wettengel, Jochen; Hoffmann, Dieter; Muenchhoff, Maximilian; Daechert, Christopher; Mairhofer, Helga; Krebs, Stefan; Fingerle, Volker; Graf, Alexander; Steininger, Philipp; Blum, Helmut; Hornung, Veit; Liebl, Bernhard; Überla, Klaus; Prelog, Martina; Knolle, Percy; Keppler, Oliver T; Protzer, Ulrike.
Afiliação
  • Wratil PR; Max von Pettenkofer Institute and Gene Center, Virology, National Reference Center for Retroviruses, Faculty of Medicine, LMU München, Munich, Germany.
  • Stern M; German Centre for Infection Research (DZIF), Partner Site, Munich, Germany.
  • Priller A; Max von Pettenkofer Institute and Gene Center, Virology, National Reference Center for Retroviruses, Faculty of Medicine, LMU München, Munich, Germany.
  • Willmann A; Institute of Molecular Immunology and Experimental Oncology, University Hospital rechts der Isar, Technical University of Munich (TUM), School of Medicine, Munich, Germany.
  • Almanzar G; Institute of Virology, Helmholtz Center Munich, TUM, School of Medicine, Munich, Germany.
  • Vogel E; Pediatric Rheumatology / Special Immunology, Pediatrics Department, University Hospital Würzburg, Würzburg, Germany.
  • Feuerherd M; Institute of Virology, Helmholtz Center Munich, TUM, School of Medicine, Munich, Germany.
  • Cheng CC; Institute of Virology, Helmholtz Center Munich, TUM, School of Medicine, Munich, Germany.
  • Yazici S; Institute of Virology, Helmholtz Center Munich, TUM, School of Medicine, Munich, Germany.
  • Christa C; Institute of Molecular Immunology and Experimental Oncology, University Hospital rechts der Isar, Technical University of Munich (TUM), School of Medicine, Munich, Germany.
  • Jeske S; Institute of Virology, Helmholtz Center Munich, TUM, School of Medicine, Munich, Germany.
  • Lupoli G; Institute of Virology, Helmholtz Center Munich, TUM, School of Medicine, Munich, Germany.
  • Vogt T; Max von Pettenkofer Institute and Gene Center, Virology, National Reference Center for Retroviruses, Faculty of Medicine, LMU München, Munich, Germany.
  • Albanese M; Pediatric Rheumatology / Special Immunology, Pediatrics Department, University Hospital Würzburg, Würzburg, Germany.
  • Mejías-Pérez E; Max von Pettenkofer Institute and Gene Center, Virology, National Reference Center for Retroviruses, Faculty of Medicine, LMU München, Munich, Germany.
  • Bauernfried S; Max von Pettenkofer Institute and Gene Center, Virology, National Reference Center for Retroviruses, Faculty of Medicine, LMU München, Munich, Germany.
  • Graf N; Gene Center and Department of Biochemistry, LMU München, Munich, Germany.
  • Mijocevic H; Institute of Virology, Helmholtz Center Munich, TUM, School of Medicine, Munich, Germany.
  • Vu M; Institute of Virology, Helmholtz Center Munich, TUM, School of Medicine, Munich, Germany.
  • Tinnefeld K; Institute of Virology, Helmholtz Center Munich, TUM, School of Medicine, Munich, Germany.
  • Wettengel J; Institute of Virology, Helmholtz Center Munich, TUM, School of Medicine, Munich, Germany.
  • Hoffmann D; German Centre for Infection Research (DZIF), Partner Site, Munich, Germany.
  • Muenchhoff M; Institute of Virology, Helmholtz Center Munich, TUM, School of Medicine, Munich, Germany.
  • Daechert C; German Centre for Infection Research (DZIF), Partner Site, Munich, Germany.
  • Mairhofer H; Institute of Virology, Helmholtz Center Munich, TUM, School of Medicine, Munich, Germany.
  • Krebs S; Max von Pettenkofer Institute and Gene Center, Virology, National Reference Center for Retroviruses, Faculty of Medicine, LMU München, Munich, Germany.
  • Fingerle V; German Centre for Infection Research (DZIF), Partner Site, Munich, Germany.
  • Graf A; Max von Pettenkofer Institute and Gene Center, Virology, National Reference Center for Retroviruses, Faculty of Medicine, LMU München, Munich, Germany.
  • Steininger P; Max von Pettenkofer Institute and Gene Center, Virology, National Reference Center for Retroviruses, Faculty of Medicine, LMU München, Munich, Germany.
  • Blum H; Laboratory for Functional Genome Analysis, Gene Center, LMU München, Munich, Germany.
  • Hornung V; Bavarian Health and Food Safety Authority (LGL), Oberschleißheim, Germany.
  • Liebl B; Laboratory for Functional Genome Analysis, Gene Center, LMU München, Munich, Germany.
  • Überla K; Institute of Clinical and Molecular Virology, University Hospital Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.
  • Prelog M; Laboratory for Functional Genome Analysis, Gene Center, LMU München, Munich, Germany.
  • Knolle P; Gene Center and Department of Biochemistry, LMU München, Munich, Germany.
  • Keppler OT; Bavarian Health and Food Safety Authority (LGL), Oberschleißheim, Germany.
  • Protzer U; Institute of Clinical and Molecular Virology, University Hospital Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.
Nat Med ; 28(3): 496-503, 2022 03.
Article em En | MEDLINE | ID: mdl-35090165
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 1_ASSA2030 / 2_ODS3 / 4_TD Problema de saúde: 1_doencas_nao_transmissiveis / 1_doencas_transmissiveis / 2_enfermedades_transmissibles / 2_muertes_prematuras_enfermedades_notrasmisibles / 4_pneumonia Assunto principal: Glicoproteína da Espícula de Coronavírus / SARS-CoV-2 / COVID-19 / Vacina BNT162 Limite: Humans Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 1_ASSA2030 / 2_ODS3 / 4_TD Problema de saúde: 1_doencas_nao_transmissiveis / 1_doencas_transmissiveis / 2_enfermedades_transmissibles / 2_muertes_prematuras_enfermedades_notrasmisibles / 4_pneumonia Assunto principal: Glicoproteína da Espícula de Coronavírus / SARS-CoV-2 / COVID-19 / Vacina BNT162 Limite: Humans Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha