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Safety and virologic impact of the IL-15 superagonist N-803 in people living with HIV: a phase 1 trial.
Miller, Jeffrey S; Davis, Zachary B; Helgeson, Erika; Reilly, Cavan; Thorkelson, Ann; Anderson, Jodi; Lima, Noemia S; Jorstad, Siri; Hart, Geoffrey T; Lee, John H; Safrit, Jeffrey T; Wong, Hing; Cooley, Sarah; Gharu, Lavina; Chung, Hyunsoo; Soon-Shiong, Patrick; Dobrowolski, Curtis; Fletcher, Courtney V; Karn, Jonathan; Douek, Daniel C; Schacker, Timothy W.
Afiliação
  • Miller JS; Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
  • Davis ZB; Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
  • Helgeson E; Division of Biostatistics, University of Minnesota School of Public Health, Minneapolis, MN, USA.
  • Reilly C; Division of Biostatistics, University of Minnesota School of Public Health, Minneapolis, MN, USA.
  • Thorkelson A; Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
  • Anderson J; Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
  • Lima NS; Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Jorstad S; Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
  • Hart GT; Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
  • Lee JH; ImmunityBio, Culver City, CA, USA.
  • Safrit JT; ImmunityBio, Culver City, CA, USA.
  • Wong H; HCW Biologics, Miramar, FL, USA.
  • Cooley S; HCW Biologics but was with Altor BioSciences at the start of the study, Miramar FL, USA.
  • Gharu L; Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
  • Chung H; Fate Therapeutics, San Diego, CA, USA.
  • Soon-Shiong P; Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Dobrowolski C; Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Fletcher CV; ImmunityBio, Culver City, CA, USA.
  • Karn J; Department of Molecular Biology and Microbiology, Medical School, Case Western Reserve University, Cleveland, OH, USA.
  • Douek DC; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory School of Medicine, Atlanta, GA, USA.
  • Schacker TW; Antiviral Pharmacology Laboratory, UNMC Center for Drug Discovery, University of Nebraska Medical Center, Omaha, NE, USA.
Nat Med ; 28(2): 392-400, 2022 02.
Article em En | MEDLINE | ID: mdl-35102335

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 2_ODS3 Problema de saúde: 2_enfermedades_transmissibles Assunto principal: Infecções por HIV / HIV-1 Limite: Humans Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 2_ODS3 Problema de saúde: 2_enfermedades_transmissibles Assunto principal: Infecções por HIV / HIV-1 Limite: Humans Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
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