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Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis.
Shen, Minhong; Wei, Yong; Kim, Hahn; Wan, Liling; Jiang, Yi-Zhou; Hang, Xiang; Raba, Michael; Remiszewski, Stacy; Rowicki, Michelle; Wu, Cheng-Guo; Wu, Songyang; Zhang, Lanjing; Lu, Xin; Yuan, Min; Smith, Heath A; Zheng, Aiping; Bertino, Joseph; Jin, John F; Xing, Yongna; Shao, Zhi-Ming; Kang, Yibin.
Afiliação
  • Shen M; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
  • Wei Y; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
  • Kim H; Department of Chemistry, Princeton University, Princeton, NJ, USA.
  • Wan L; Princeton University Small Molecule Screening Center, Princeton University, Princeton, NJ, USA.
  • Jiang YZ; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
  • Hang X; Key Laboratory of Breast Cancer in Shanghai, Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, P.R. China.
  • Raba M; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
  • Remiszewski S; Crelux GmgH, Martinsried, Germany.
  • Rowicki M; SWR Pharma Consulting LLC, Princeton, NJ, USA.
  • Wu CG; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
  • Wu S; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, WI, USA.
  • Zhang L; Key Laboratory of Breast Cancer in Shanghai, Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, P.R. China.
  • Lu X; Department of Pathology, University Medical Center of Princeton, Plainsboro, NJ, USA.
  • Yuan M; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
  • Smith HA; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
  • Zheng A; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
  • Bertino J; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
  • Jin JF; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, WI, USA.
  • Xing Y; Pharmacokinetics and Pharmacodynamics (PK/PD) Shared Resource, Rutgers Cancer Institute of New Jersey Rutgers, The State University of New Jersey, New Brunswick, NJ, USA.
  • Shao ZM; Robert Wood Johnson Medical School Rutgers, The State University of New Jersey, New Brunswick, NJ, USA.
  • Kang Y; Firebrand Therapeutics, Princeton, NJ, USA.
Nat Cancer ; 3(1): 43-59, 2022 01.
Article em En | MEDLINE | ID: mdl-35121987
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Ligação a RNA / Endonucleases / Neoplasias de Mama Triplo Negativas / Proteínas de Membrana / Nuclease do Micrococo Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Cancer Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Ligação a RNA / Endonucleases / Neoplasias de Mama Triplo Negativas / Proteínas de Membrana / Nuclease do Micrococo Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Cancer Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos