Group sequential designs for in vivo studies: Minimizing animal numbers and handling uncertainty in power analysis.

Blotwijk, Susanne; Hernot, Sophie; Barbé, Kurt

Blotwijk, Susanne; Hernot, Sophie; Barbé, Kurt.

Afiliação

Blotwijk S; Biostatistics and Medical Informatics Research Group (BISI), Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium. Electronic address: susanne.blotwijk@vub.be.
Hernot S; Laboratory for In vivo Cellular and Molecular Imaging, (ICMI-BEFY/MIMA), Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium.
Barbé K; Biostatistics and Medical Informatics Research Group (BISI), Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium.

Res Vet Sci ; 145: 248-254, 2022 Jul.

Article em En | MEDLINE | ID: mdl-35299085

Assuntos

Projetos de Pesquisa; Análise de Variância; Animais; Incerteza

Palavras-chave

Animal; Experimental design; Group sequential design; Interim analysis; Preclinical; Reduction

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Projetos de Pesquisa Limite: Animals Idioma: En Revista: Res Vet Sci Ano de publicação: 2022 Tipo de documento: Article

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