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Drug-like molecules with anti-trypanothione synthetase activity identified by high throughput screening.
Benítez, Diego; Franco, Jaime; Sardi, Florencia; Leyva, Alejandro; Durán, Rosario; Choi, Gahee; Yang, Gyongseon; Kim, Taehee; Kim, Namyoul; Heo, Jinyeong; Kim, Kideok; Lee, Honggun; Choi, Inhee; Radu, Constantin; Shum, David; No, Joo Hwan; Comini, Marcelo A.
Afiliação
  • Benítez D; Laboratory Redox Biology of Trypanosomes, Institut Pasteur de Montevideo, Montevideo, Uruguay.
  • Franco J; Laboratory Redox Biology of Trypanosomes, Institut Pasteur de Montevideo, Montevideo, Uruguay.
  • Sardi F; Laboratory Redox Biology of Trypanosomes, Institut Pasteur de Montevideo, Montevideo, Uruguay.
  • Leyva A; Analytical Biochemistry and Proteomics Unit, Institut Pasteur de Montevideo, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay.
  • Durán R; Analytical Biochemistry and Proteomics Unit, Institut Pasteur de Montevideo, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay.
  • Choi G; Host-Parasite Research Laboratory, Institut Pasteur Korea, Gyeonggi-do, Republic of Korea.
  • Yang G; Host-Parasite Research Laboratory, Institut Pasteur Korea, Gyeonggi-do, Republic of Korea.
  • Kim T; Assay Development and Screening, Institut Pasteur Korea, Gyeonggi-do, Republic of Korea.
  • Kim N; Assay Development and Screening, Institut Pasteur Korea, Gyeonggi-do, Republic of Korea.
  • Heo J; Assay Development and Screening, Institut Pasteur Korea, Gyeonggi-do, Republic of Korea.
  • Kim K; Automation and Logistics Management, Institut Pasteur Korea, Gyeonggi-do, Republic of Korea.
  • Lee H; Automation and Logistics Management, Institut Pasteur Korea, Gyeonggi-do, Republic of Korea.
  • Choi I; Medicinal Chemistry, Institut Pasteur Korea, Gyeonggi-do, Republic of Korea.
  • Radu C; Automation and Logistics Management, Institut Pasteur Korea, Gyeonggi-do, Republic of Korea.
  • Shum D; Assay Development and Screening, Institut Pasteur Korea, Gyeonggi-do, Republic of Korea.
  • No JH; Host-Parasite Research Laboratory, Institut Pasteur Korea, Gyeonggi-do, Republic of Korea.
  • Comini MA; Laboratory Redox Biology of Trypanosomes, Institut Pasteur de Montevideo, Montevideo, Uruguay.
J Enzyme Inhib Med Chem ; 37(1): 912-929, 2022 Dec.
Article em En | MEDLINE | ID: mdl-35306933
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 3_ND Problema de saúde: 3_chagas_disease / 3_neglected_diseases Assunto principal: Trypanosoma cruzi / Leishmania infantum / Amida Sintases / Antineoplásicos / Antiprotozoários Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Revista: J Enzyme Inhib Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Uruguai
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 3_ND Problema de saúde: 3_chagas_disease / 3_neglected_diseases Assunto principal: Trypanosoma cruzi / Leishmania infantum / Amida Sintases / Antineoplásicos / Antiprotozoários Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Revista: J Enzyme Inhib Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Uruguai