[Peripheral blood T-lymphocytes of patients with chronic B-cell lympholeukemia express Ia-like antigens]. / T-limfotsity perifericheskoi krovi bol'nykh B-kletochnym khronicheskim limfoleikozom ékspressiruiut Ia-podobnye antigeny.
Biull Eksp Biol Med
; 103(2): 196-8, 1987 Feb.
Article
em Ru
| MEDLINE
| ID: mdl-3545318
ABSTRACT
15.7 +/- 3.5% of sheep rosette-forming cells (SRFC) were isolated from the peripheral blood of 11 patients with B-cell chronic lympholeukemia (B-CLL). SRFC did not express surface immunoglobulins, antigens of nondifferentiated blasts and antigens of early T-cell precursors, while NK-cell antigen expression was low. 6 of 11 patients revealed 44.6 +/- 19.6% of Ia-like antigens in SRFC. Ia-like antigen expression was 4.8 +/- 0.6% in SRFC isolated from the peripheral blood of 19 healthy donors. The expression of Ia-like antigens in T cells of patients with B-CLL is suggested to be related to the activation of regulatory T-lymphocyte subpopulation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Linfócitos T
/
Leucemia Linfoide
/
Antígenos de Histocompatibilidade Classe II
Limite:
Humans
Idioma:
Ru
Revista:
Biull Eksp Biol Med
Ano de publicação:
1987
Tipo de documento:
Article