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Synthesis and biological evaluation of nusbiarylin derivatives as bacterial rRNA synthesis inhibitor with potent antimicrobial activity against MRSA and VRSA.
Qiu, Yangyi; Chu, Adrian Jun; Tsang, Tsz Fung; Zheng, Yingbo; Lam, Nga Man; Li, Kendra Sek Lam; Ip, Margaret; Yang, Xiao; Ma, Cong.
Afiliação
  • Qiu Y; State Key Laboratory of Chemical Biology and Drug Discovery, and Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Kowloon, Hong Kong Special Administrative Region of China.
  • Chu AJ; Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong Special Administrative Region of China.
  • Tsang TF; Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong Special Administrative Region of China.
  • Zheng Y; State Key Laboratory of Chemical Biology and Drug Discovery, and Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Kowloon, Hong Kong Special Administrative Region of China.
  • Lam NM; Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong Special Administrative Region of China.
  • Li KSL; Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong Special Administrative Region of China.
  • Ip M; Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong Special Administrative Region of China.
  • Yang X; Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong Special Administrative Region of China.
  • Ma C; State Key Laboratory of Chemical Biology and Drug Discovery, and Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Kowloon, Hong Kong Special Administrative Region of China.
Bioorg Chem ; 124: 105863, 2022 07.
Article em En | MEDLINE | ID: mdl-35580381
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Staphylococcus aureus Resistente à Meticilina Tipo de estudo: Guideline / Prognostic_studies Idioma: En Revista: Bioorg Chem Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Staphylococcus aureus Resistente à Meticilina Tipo de estudo: Guideline / Prognostic_studies Idioma: En Revista: Bioorg Chem Ano de publicação: 2022 Tipo de documento: Article